Inflammasomes: Mechanism of Action, Regulation and Role in Disease

The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL1ß takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this finetuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections.

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Inflammasomes: Mechanism of Action, Regulation and Role in Disease

The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL1ß takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this finetuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections.

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Inflammasomes: Mechanism of Action, Regulation and Role in Disease

Inflammasomes: Mechanism of Action, Regulation and Role in Disease

by Angie Mason
Inflammasomes: Mechanism of Action, Regulation and Role in Disease

Inflammasomes: Mechanism of Action, Regulation and Role in Disease

by Angie Mason

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Overview

The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL1ß takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this finetuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections.


Product Details

ISBN-13: 9781634848916
Publisher: Nova Science Publishers, Incorporated
Publication date: 06/07/2016
Series: Biotechnology in Agriculture, Industry and Medicine
Pages: 90
Product dimensions: 6.00(w) x 1.25(h) x 9.00(d)
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