In-Vitro Fertilization

by Kay Elder, Brian Dale, Yves Ménézo (Contribution by), Joyce Harper (Contribution by), John Huntriss (Contribution by)

Overview

This fully updated new edition of a successful and popular practical guide is an indispensable account of modern in-vitro fertilization practice. Initial chapters cover theoretical aspects of gametogenesis and embryo development at the cellular and molecular level, while the latter half of the book describes the requisites for a successful IVF laboratory and the basic technologies in ART. Advanced techniques, including pre-implantation genetic diagnosis, vitrification and stem-cell technology, are comprehensively covered, providing up-to-date analyses of these groundbreaking technologies. This edition includes: • New practical techniques, including preservation of fertility for cancer patients, stem-cell biology/technology, vitrification and in-vitro maturation • A 'refresher' study review of fundamental principles of cell and molecular biology • The latest information available from animal and human research in reproductive biology Packed with a wealth of practical and scientific detail, this is a must for all IVF practitioners.

Product Details

ISBN-13:	9780511993657
Publisher:	Cambridge University Press
Publication date:	12/02/2010
Sold by:	Barnes & Noble
Format:	eBook
File size:	5 MB

About the Author

Kay Elder is Senior Research Scientist, Bourn Hall Clinic, Bourn, Cambridge, UK.
Brian Dale is Director of the Centre for Assisted Fertilization, Clinica Villa del Sole, Naples, Italy.

Table of Contents

Preface; 1. Review of cell and molecular biology; 2. Endocrine control of reproduction: Controlled Ovarian Hyperstimulation for ART; 3. Gametes and gametogenesis; 4. Sperm-oocyte interaction; 5. First stages of development; 6. Implantation and early stages of fetal development; 7. Stem cell biology; 8. The clinical in vitro fertilization laboratory; 9. Quality management in the IVF laboratory; 10. Sperm and ART; 11. Oocyte retrieval and embryo culture; 12. Cryopreservation of gametes and embryos; 13. Micromanipulation techniques; 14. Preimplantation genetic diagnosis Joyce Harper; 15. Epigenetics and assisted reproduction John Huntriss; Index.

Editorial Reviews

Reviewer: Kasey Reynolds, MD (Washington University School of Medicine)
Description: This textbook is a comprehensive review of in vitro fertilization, encompassing not only descriptions of current techniques but also the physiology and biology behind the technology. This is a 3rd edition text; the 2nd edition was published 2000.
Purpose: According to the authors, the purpose is to "distill large bodies of information relevant to human IVF into a comprehensive background of physiological, biochemical, and physical principles that provide the scientific foundation for well-established protocols in current use." In short, the authors recognize that the field of IVF is continuously expanding its horizons and, although there is a tremendous amount of information on individual topics in both journals and books, there is a relative paucity of books that cover the science behind, and techniques involved in, IVF.
Audience: The book seems geared for students new to IVF and reproductive technology. It is an appropriate book for fellows entering the field and looking for a knowledge base upon which to build, or even for residents on a subspecialty rotation looking to enhance their fundamental knowledge. It also may be appropriate for certain basic scientists who are exceedingly familiar with some aspects of reproductive technology, but who also need a more general primer on the entire process involved in IVF from start to finish.
Features: This is a comprehensive review of the process of IVF, from the science behind the process, to basic gamete biology, to reproductive physiology. Following an introduction to the science behind the process, which gives readers an improved understanding of the technology, the book continues with an overview of the techniques of IVF and the current technology involved in IVF and ART, and a behind-the-scenes glimpse into the IVF laboratory. This book is successful in comprehensively reviewing most aspects of reproductive technology, but in a concise manner so that readers do not get overwhelmed with details.
Assessment: This is a quality book that has achieved its goal of enlightening readers about the process of IVF, and it will be useful to many different audiences, from basic scientists to fellows to clinicians. The science of IVF and ART is always evolving, as this book rightly acknowledges in the preface, and readers should recognize the need for updated editions.

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