Image-Guided High-Precision Radiotherapy

by Esther G. C. Troost (Editor)

Overview

This book equips readers with detailed knowledge on the current status of image-guided radiotherapy with photons and particles and highlights issues that need to be addressed in order to further improve treatment outcomes. The opening chapters cover clinical and technical aspects of target volume definition using anatomic (computed tomography and magnetic resonance imaging; MRI) as well as functional (MRI and positron emission tomography) imaging. Up-to-date information is then provided on the full range of image-guided high-precision radiotherapy techniques, including IMRT/VMAT, stereotactic body radiation therapy, MR-guided linear accelerators, MR-guided brachytherapy, and particle therapy. The role of ultrasonography in image-guided radiotherapy is discussed, as are the available means for target volume demarcation and stabilization and adaptive radiation therapy. Finally, outcome evaluation is explored in depth, with a particular focus on the role of multimodality imaging in predicting tumor control and normal tissue toxicity. The authors are experts in different specialties and the book will be of high value for radiation oncologists, medical physicists, radiologists, nuclear medicine physicians, and radiation technicians.

Product Details

ISBN-13:	9783031086007
Publisher:	Springer International Publishing
Publication date:	10/11/2022
Edition description:	2022
Pages:	315
Product dimensions:	6.10(w) x 9.25(h) x (d)

About the Author

Esther Troost, MD, PhD, is a radiation oncologist, chair of the Department of Radiotherapy and Radiation Oncology of the University Hospital Carl Gustav Carus, professor of image-guided high-precision radiation therapy at the Faculty of Medicine of the Technische Universität Dresden, Germany, and group leader at the Helmholtz-Zentrum Dresden-Rossendorf, Germany. She focuses on incorporating anatomical and functional imaging in radiation treatment planning and early response evaluation for personalised treatment and on exploiting imaging changes as objective measures of tumor response. Professor Troost is a reviewer for numerous international scientific journals, a member of national and international societies, and director of the European Society for Radiotherapy and Oncology (ESTRO) teaching course on “Target volume delineation”.

Table of Contents

PART I) TARGET VOLUME DEFINITION.- Chapter 1) Use of [18F] FDG-PET for target volume definition in radiotherapy.- Chapter 2) Specific PET tracers for solid tumors and for definition of the biological target volume.- Chapter 3) Use of anatomical and functional MRI in radiation treatment planning-. PART II) IMAGE-GUIDED RT TECHNIQUES.- Chapter 4) In-room systems for patient positioning and motion control.- Chapter 5) IMRT/VMAT, SABR.- Chapter 6) Magnetic resonance-guided adaptive radiotherapy – technical concepts.- Chapter 7) MR-integrated linear accelerators – first clinical results.- Chapter 8) Image-guided adaptive brachytherapy.- Chapter 9) Ultrasonography in image-guided radiotherapy – current status and future challenges.- Chapter 10) Means for target volume delineation and stabilisation: fiducial markers, balloons, and others.- Chapter 11) Artificial intelligence in radiation oncology: a rapidly evolving picture.- PART III) OUTCOME EVALUATION.- Chapter 12) Multimodality imaging for prediction of tumour control following radiotherapy.- Chapter 13) Modelling for radiation treatment outcome.

Editorial Reviews

Reviewer: Mark D. Hurwitz, MD (New York Medical College)
Description: The book covers a wide range of topics pertaining to image guidance for high-precision radiation therapy.
Purpose: According to the preface, the book intends to provide readers with an overview of several topics categorized by target definitions, treatment delivery, and outcome evaluation, which are worthy, albeit broad, topics. The book is valuable as a consolidated resource.
Audience: The target audience of the book includes trainees, whether radiation therapy students, physics students, or medical residents. The authors also state the book is, in part, intended for individuals outside the field with interest in image guidance. The authors appear to be credible authorities on the subject matter.
Features: The book is divided into three parts: Target Definition, Image-Guided Radiation Therapy Techniques, and Outcome Evaluation. The book consolidates wide-ranging topics into a single resource, which is impressive given the amount of commercial information available on the platforms discussed. One strength of this book is the unbiased presentation of competing technologies, providing the pros and cons associated with each. With a heavy emphasis on evolving technology, the book stays current by highlighting topics such as clinical application of MR in treatment delivery. However, the book contains no index to help readers locate specific information of interest.
Assessment: This book contains a strong collection of information on topics related to image-guided high-precision radiation therapy. Trainees in particular will find the book of interest, especially with respect to the benefits and limitations of competing technologies available in the field today.

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