Histological Diagnosis of Nevi and Melanoma / Edition 2

by Guido Massi, Philip E. LeBoit

Overview

The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The second edition of this text and atlas depicts a broad range of the most important and most challenging melanocytic lesions. Each individual case is illustrated with at least three high-quality color photographs and is commented on at length, highlighting the diagnostic clues. The goal of the authors is to assist the ordinary pathologist in making a precise workable diagnosis in their daily practice. They achieve this by providing simple criteria that will serve as a sound basis for an unequivocal diagnosis of either a benign or a malignant melanocytic neoplasm. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.

Product Details

ISBN-13:	9783642373107
Publisher:	Springer Berlin Heidelberg
Publication date:	09/17/2013
Edition description:	2nd ed. 2014
Pages:	752
Product dimensions:	15.10(w) x 11.50(h) x 1.90(d)

About the Author

Guido Massi, MD, graduated in Medicine and Surgery at the Catholic University School of Medicine, Rome, Italy in 1975 and subsequently obtained his Specialization in Pathology and Specialization in Dermatology from the same institution. He has been an Associate Professor of Pathology and Dermatopathology at the School since 1999. He is also Chief of the Surgical Pathology Laboratory (which mainly deals with dermatopathology) at the Complesso Integrato Columbus in Rome and Director of the Dermatopathology Section of Laboratorio Inghirami, Rome. Dr. Massi has been responsible for the organization of a number of international workshops and symposia on dermatopathology. He is the author or co-author of three previous books as well as many publications in peer-reviewed journals that address a wide range of dermatological conditions.

Philip E. LeBoit, MD, studied at Albany Medical College, New York, before serving as a Resident in Pathology, Fellow in Dermatopathology, and Resident in Laboratory Medicine. Since 1997 he has been Professor of Pathology in the Departments of Pathology and Dermatology, University of California, San Francisco, where he is also Division Chief of the Dermatopathology Section and Co-director of the Dermatopathology Service. He has received various awards, including the A. Bernard Ackerman Lecture Award from the International Society of Dermatopathology and both the Herman Pinkus Memorial Lecture Award and Founders’ Awards from the American Society of Dermatopathology. He is a member of various editorial boards, including of the American Journal of Dermatopathology (former editor in chief), American Journal of Surgical Pathology, Dermatology: Practical & Conceptual, skinnet.com, and Derm101.com. Dr. LeBoit was President of the International Society of Dermatopathology from 2007-10 and is a member of the UICC TNM Expert Panel on Skin Cancer. He is the first author or co-author of approaching 150 original articlesas well as many editorials, review articles and book chapters.

Table of Contents

Criteria for the Diagnosis of Benign Melanocytic Nevus.- Melanocytic Hyperplasia.- Melanotic Macules.- “Commonon” Nevus.- Congenital Nevus.- Junctional Anomalies in Congenital and Acquired Nevi in the First Year of Life.- Proliferative Nodules in Congenital Nevi.- Nevus Spilus.- Dermal Melanocytoses.- “Common “Blue Nevus.- “Cellular” Blue Nevus.- SPITZ Nevus.- Reed Nevus.- Deep Penetrating Nevus.- Dysplastic & Clarks’s Nevus.- Combinedin Nevus.- Nevi on Acral Skin.- Nevi on Genital Skin.- Nevi in the Oral Cavity.- Polypoid Nevus of Pregnancy and Milk Line Nevi.- Nevi OF the Conjunctiva.- Melanocytic Nevi Affected by inflammatory Skin Dideases.- Halo Nevus.- Recurrent and Persistent Nevus.- Traumatised Nevi.- Benign Melanocytoma.- Medicolegal Cases.- Criteria for the Diagnosis OF Malignant Melanoma.- Melanoma in situ.- Lentigo Maligna.- Superficial Spreading Pattern of Melanoma.- Nodular Pattern of Melanoma.- Melanoma with Spindle Cell.- Nevoid Melanoma.- Spitzoid Melanoma.- Desmoplastic Melanoma.- Neurotropic Melanoma.- Melanoma with Neural Differentiaton.- Myxoid Melanoma.- Melanoma with Features of Blue Nevus.- Animal Type Melanoma.- Melanoma on Blue Nevus.- Unusual and Bizarre forms of Melanoma.- Melanoma on Nevus.- Melanoma on Palms, Soles and Subungual Bed.- Melanoma on Genital Skin.- Melanoma on Oral Cavity.- Melanoma on Conjunctiva.- Recurrent and Persistent Melanoma.- Regressing and Regressed Melanoma.- Cutaneous Metastatic Melanoma.- Malignant Melanocytoma.- Medicolegal Cases.- Molecular Biology in the Diagnosis of Nevi and Melanoma.- Histological Prognostic Factors.

Editorial Reviews

Reviewer: Susan M. Swetter, M.D.(Stanford University Medical Center)
Description: This is the second edition of a comprehensive overview of both benign and malignant melanocytic proliferations that focuses on histopathological diagnosis, differential diagnosis, and histomorphological features of melanoma and melanocytic nevi. The easy-to-understand format combines the clinical and histological description for each entity, followed by numerous photomicrographs of the histology. For controversial melanocytic neoplasms, such as dysplastic nevi, the authors combine published data with their vast experience to present a rational approach to histological diagnosis and the implications for clinical management.
Purpose: The aim is to provide a detailed color atlas and book that contains ample illustrations of melanocytic lesions, while emphasizing histological features that distinguish benign nevi from melanoma. Both common examples and variants of the most important and/or challenging melanocytic lesions are included. Melanocytic lesions encountered in daily practice are described, as well as more challenging melanocytic lesions and/or melanoma subtypes. The book provides a logical, practical classification of melanocytic lesions, using the terminology most frequently used in dermatopathology laboratories. The contributions of molecular biology and the sentinel node technique are incorporated into diagnostic classifications and algorithms. This is a necessary book that provides useful information for both clinicians and pathologists.
Audience: The audience is general pathologists, dermatopathologists, and practitioners specializing in melanoma, including dermatologists, surgeons, and oncologists, as well as researchers in the field. Residents in pathology and dermatology will appreciate the format and high-quality photomicrographs presented along with key features and diagnostic clues. The contributing authors are internationally recognized for their dermatopathology acumen and scientific expertise in the diagnosis of melanoma, melanocytic nevi, and atypical melanocytic neoplasms.
Features: This is an in-depth resource on diagnostic features of melanocytic nevi, melanoma, and challenging atypical melanocytic neoplasms, including spitzoid melanoma of infancy, junctional anomalies in children, melanocytoma, variants of Spitz's nevi, and atypical cellular blue nevi. The format is readily accessible to both pathologists and clinicians, with a short introduction for each entity, followed by a brief description of clinical and then histological features. Abundant photomicrographs are used to illustrate common melanocytic lesions, melanoma, and rare melanocytic variants, with at least three high-quality color photographs (from low to higher magnifications) and accompanying text that highlights the diagnostic clues.
Assessment: There are few books devoted to the topic of histopathological diagnosis of common, atypical, benign, and/or malignant melanocytic neoplasms, and none that present the information so clearly. The introduction to each entity provides the historical context of histological diagnosis of the lesion, with frequent commentary on how pathology relates to clinical outcome. This is followed by a succinct presentation of the histological features as well as the differential diagnosis, to provide the optimal diagnostic algorithm for practitioners. The numerous photomicrographs are superb. This is a unique, comprehensive source of information for melanocytic lesion histopathology, and a likely must have for pathologists, dermatopathologists, and dermatologists.

Doody's Review Service

From the reviews of the second edition:

“The book provides a logical, practical classification of melanocytic lesions, using the terminology most frequently used in dermatopathology laboratories. … This is a necessary book that provides useful information for both clinicians and pathologists. … This is a unique, comprehensive source of information for melanocytic lesion histopathology, and a likely must have for pathologists, dermatopathologists, and dermatologists.” (Susan M. Swetter, Doody’s Book Reviews, April, 2014)

From the Publisher

4 Stars! from Doody