Harrison's Principles of Internal Medicine, Twenty-First Edition (Vol.1 & Vol.2)

by J. Larry Jameson, Stephen Hauser, Dan Longo, Dennis L. Kasper, Joseph Loscalzo

Overview

The Voice of Clinical Reason

A Doody's Core Title for 2023!
Harrison’s Principles of Internal Medicine is the world's most trusted clinical medicine text—and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine.

Written and edited by the world’s top experts in their respective fields, this landmark guide provides comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease.

Harrison’s is world-renowned as the most authoritative source for:

• Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases
• The physiologic and etiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow
• Updated clinical trial results and recommended guidelines
• Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings
• Coverage of both therapeutic approaches and specific treatment regimens
• Practical clinical decision trees and algorithms
• Organ/system-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, and general and specific approaches to therapy

Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition:

• Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer
• Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries
• More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes
• Numerous atlases featuring curated collections of important visual aspects of diagnosis and management
• Updated and time-saving curation and synthesis of established and new medical literature and studies
• Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms

Product Details

ISBN-13:	9781264268504
Publisher:	McGraw Hill LLC
Publication date:	03/28/2022
Edition description:	21st ed.
Pages:	2
Sales rank:	45,001
Product dimensions:	8.80(w) x 11.10(h) x 4.60(d)

About the Author

McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

Dennis L. Kasper, MD, MA (Hon)William Ellery Channing Professor of MedicineProfessor of Microbiology and Molecular GeneticsExecutive Dean for Academic ProgramsHarvard Medical SchoolDirector, Channing LaboratoryDepartment of MedicineBrigham and Women’s Hospital

Joseph Loscalzo, MD, PhD, is Hersey Professor of the Theory and Practice of Medicine at Harvard Medical School, Chairman of the Department of Medicine, and Physician-in-Chief at Brigham and Women's Hospital.
Anthony S. Fauci, MD, is Chief of the Laboratory of Immunoregulation and Director of the National Institutes of Allergy and Infectious Diseases for the National Institutes of Health.
Dennis L. Kasper, MD, is William Emery Channing Professor of Medicine and Professor of Microbiology and Molecular Genetics at Harvard Medical School.
Stephen L. Hauser, MD, is Robert A. Fishman Distinguished Professor of Neurology and Director of the UCSF Weill Institute for Neurosciences for the University of California, San Francisco.
Dan L. Longo, MD, is Professor of Medicine at Harvard University School of Medicine and Deputy Editor of Oncology for the New England Journal of Medicine.
J. Larry Jameson, MD, PhD, is Robert G. Dunlop Professor of Medicine; Dean of Raymond and Ruth Perelman School of Medicine; and Executive Vice President of the University of Pennsylvania for the Health System.

Anthony S. Fauci, MDChief, Laboratory of ImmunoregulationDirector, National Institute of Allergy and Infectious DiseasesNational Institutes of Health. In 2008, Dr. Fauci was awarded the Presidential Medal of Freedom, the Nation's highest civil award.

Editorial Reviews

Reviewer: Alan I Schwartzstein, BS, MD, FAAFP, ABFM Diplomate(SSM Health Dean Medical Group)
Description: This 21st edition arrives four years after the last edition, a time during which there have been significant advances in the understanding of health, along with the existence, prevention, and therapy of disease. The tome is divided into five sections, the first being an introduction to the profession of medicine along with current issues affecting the provision of health care. The second portion includes a valuable symptom and sign orientation to diagnosis, while the third and largest portion orients focus on the organ system and disease groups and the conditions in each. Each of these begins with an "approach" to (organ) diagnosis and treatment. The final portion of the book covers many issues not covered in the previous portion, such as poisoning and drug overdose, environmental illness, and a very impressive chapter on the approach to aging and care of geriatric patients.
Purpose: The purpose of this book is to serve as a comprehensive reference source on health and disease with a focus on practicing physicians and clinical presentations, summaries of psychophysiology, and treatment, as well as highlights of emerging frontiers of medicine and science. This is a worthy objective for primary care physicians as well as subspecialty clinicians who may provide diagnosis and treatment for these conditions, and the authors have met this goal admirably. As a family physician, this book meets my need for a reference that is easily accessible for my purposes, even if it does not have bedside/exam room value.
Audience: The audience for this book, according to the authors, is "learners throughout their careers." The book meets the needs of those in training, as it has for generations of physicians. For practicing physicians in adult medicine, the book is an excellent, authoritative, up-to-date source of medical knowledge. I like the balance between comprehensiveness and accessibility, which is useful for primary care clinicians without time for more complex, scientific tomes. The authors, many of whom wrote sections of previous editions, are recognized as experts in healthcare education and clinical application.
Features: I reviewed several chapters of the book, some of which had disease entities included in the differential diagnosis for patients in my practice. The writing is less academic and more accessible for the average clinical physician than prior editions. The first chapter on the practice of medicine nicely lays out the nature of our field as an art as well as a science. Another excellent pair of chapters toward the end of the book are on the aging process and geriatrics, which include important topics such as symptomatic care and addressing the ethical and moral issues that arise in these patients and families.
Assessment: This 21st edition will be a valuable resource on the bookshelf of any adult medicine physician. There are also many videos available online with the purchase of the book, making the price tag more understandable. For those who see predominantly older patients with complex presentations, particularly in rural and urban underserved areas, it is worth updating to this edition. If not, perhaps the 20th edition combined with CME such as UpToDate, the Medical and Prescriber's Letter, and live CME will suffice until the next edition.

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