Handbook of Prebiotics / Edition 1

by Glenn R. Gibson, Marcel Roberfroid

Overview

In order to achieve optimal digestion, absorption, and nutritional health, we must have appropriate populations of positive microflora. Prebiotics are functional foods that improve health by fortifying indigenous probiotics within the gut. This fast-growing area of nutrition and microbiology is rapidly amassing data and answering many questions about the necessity and benefit of such functional foods.

Gathering contributions from leading experts in a range of disciplines, Handbook of Prebiotics presents a balanced view of the current knowledge in many different areas of the field. It discusses concept, definition and criteria for classification of a food component as prebiotics It then describes interactions with gut microbiota. Highlighting varying levels of evidence and agreement, the book presents current arguments for and against prebiotic intake. Contributions discuss the biomechanics of prebiotics and their effects on immune status, serum lipid concentrations, mineral bioavailability, and satiety modulation. They consider the health implications of prebiotic intake such as reduced incidence of gastroenteritis and chronic pathogenic gut disorders, including intestinal cancers and inflammatory bowel diseases.

Providing well-rounded coverage, the book explores the varying effects of prebiotics in different populations and age groups such as infants and the elderly, as well as livestock and pets. The final chapters describe food avenues and the safety implications for prebiotic use. Spanning several disciplines including food science, nutrition, microbiology, biotechnology, and the health sciences, this seminal work makes a point to include sound research science and well-balanced views on the potential of prebiotics for promoting good health.

Product Details

ISBN-13:	9780367387785
Publisher:	Taylor & Francis
Publication date:	09/23/2019
Edition description:	Reprint
Pages:	504
Product dimensions:	6.12(w) x 9.19(h) x (d)

About the Author

Glenn R. Gibson, Marcel B. Roberfroid

Table of Contents

Preface ix

Acknowledgments xi

Editors xiii

Contributors xv

1 General Introduction: Prebiotics in Nutrition Marcel B. Roberfroid 1

2 Gastrointestinal Microflora and Interactions with Gut Mucosa Andrew L. Wells Delphine M. A. Saulnier Glenn R. Gibson 13

3 Prebiotics: Concept, Definition, Criteria, Methodologies, and Products Marcel B. Roberfroid 39

4 The Prebiotic Effect: Review of Experimental and Human Data Sofia Kolida Glenn R. Gibson 69

5 Effects of Prebiotics on Mineral Absorption: Mechanisms of Action Ian J. Griffin Steven A. Abrams 93

6 Prebiotics and the Absorption of Minerals: A Review of Experimental and Human Data Keli M. Hawthorne Steven A. Abrams 105

7 Immune Functions and Mechanisms in the Gastrointestinal Tract Alix Dubert-Ferrandon David S. Newburg Allan W. Walker 115

8 Prebiotics and the Immune System: Review of Experimental and Human Data Stephanie Seifert Bernhard Watzl 143

9 Triacylglycerols and Cholesterol Metabolism Michel Beylot Fabien Forcheron Dominique Letexier 163

10 Prebiotics and Lipid Metabolism: Review of Experimental and Human Data Nathalie M. Delzenne Audrey Marline Neyrinck 201

11 Endocrinology of the Gastrointestinal Tract and Modulation of Satiety: Specific Focus on Glucagon-Like Peptide-1 Rémy Burcelin Patrice D. Cani 219

12 Prebiotics and Modulation of Gastrointestinal Peptides Patrice D. Cani Rémy Burcelin Claude Knauf 247

13 Designing Studies and Rodent Models for Studying Prebiotics for Colorectal Cancer Prevention Umar Asad Nancy J. Emenaker John A. Milner 263

14 Colorectal Cancer Prevention: The Role of Prebiotics Umar Asad Nancy J. Emenaker John A. Milner 285

15 Prebiotics and Reduction of Risk of Carcinogenesis: Review of Experimental and Human Data Annett Klinder Michael Glei Beatrice L. Pool-Zobel 295

16 Prebiotics and Cancer Therapy Henryk S. Taper Marcel B. Roberfroid 329

17 Pathophysiology of Inflammatory Bowel Diseases Frank Hoentjen Levinus A. Dieleman 341

18 Prebiotics in Inflammatory Bowel Diseases Francisco Guarner 375

19 Prebiotics and Infant Nutrition Yvan Vandenplas Thierry Devreker Silvia Salvatore Bruno Hauser 393

20 Prebiotics and Nutrition in the Elderly: The Concept of Healthy Ageing Ian Rowland Chris Gill 405

21 Prebiotics and Animal Nutrition Jan Van Loo Dieter Vancraeynest 421

22 Food Applications of Prebiotics Anne Franck 437

23 Prebiotics and Food Safety Gerard Pascal 449

24 Concluding Remarks Glenn R. Gibson Marcel B. Roberfroid 471

Index 475

Editorial Reviews

"I would strongly recommend this book for food scientists, gastroenterologists interested in intestinal microecology, and anyone working in the prebiotic and probiotic industry."

– Martin H. Floch, Section of Digestive Diseases, Yale University School of Medicine, in Journal of Clinical Gastroenterology, Nov/ Dec 2008, Vol. 42, No. 10

From the Publisher