Handbook of Nanoindentation: With Biological Applications / Edition 1

by Michelle L. Oyen

Overview

Nanoindentation is ideal for the characterization of inhomogeneous biological materials. However, the use of nanoindentation techniques in biological systems is associated with some distinctively different techniques and challenges. The book presents the basic science of nanoindentation, including the background of contact mechanics underlying indentation technique and the instrumentation used to gather mechanical data. It provides perspectives that are optimized for biological applications, including discussions on hydrated materials and adaptations for low-stiffness materials. The book also covers the applications of nanoindentation technique in biological materials. Highlighting current challenges, it concludes with an insightful forecast of the future.

Product Details

ISBN-13:	9789814241892
Publisher:	Jenny Stanford Publishing
Publication date:	10/31/2010
Pages:	358
Product dimensions:	6.70(w) x 9.80(h) x 0.90(d)

About the Author

Michelle L. Oyen is a Lecturer in Mechanics of Biological Materials in the Mechanics and Materials Division and the Engineering for the Life Sciences group in the Cambridge University Engineering Department. She holds a BS degree in Materials Science and Engineering and an MS Degree in Engineering Mechanics, both from Michigan State University, and a PhD degree in Biophysical Sciences and Medical Physics from the University of Minnesota. She joined Cambridge Engineering in 2006 following an appointment as Research Scientist at the University of Virginia Center for Applied Biomechanics. She is a member of the Materials Research Society and the ASME Bioengineering Division, a principal editor for the Journal of Materials Research, a moderator of iMechanica and a founding committee member for the new UK-based bioengineering society.

Table of Contents

Preface v

Chapter 1 Introduction Tamaryn A. V. Shean Michelle L. Oyen Michael F. Ashby 1

Chapter 2 Indentation and Adhesion at Small Length Scales Robert F. Cook 23

Chapter 3 Instrumentation and Experimentation Kryslyn J. Van Vliet 39

Chapter 4 Mechanics of Adhesion Robert F. Cook 77

Chapter 5 Mechanics of Indentation Michelle L. Oyen 123

Chapter 6 Computational Modeling of Indentation Xi Chen 153

Chapter 7 Nanoindentation of Bone Virginia L. Ferguson Sara E. Olesiak 185

Chapter 8 Nanoindentation of Tooth Tissues Li-Hong He Michael V. Swain 239

Chapter 9 Nanoindentation of Soft Tissues and Other Biological Materials Donna M. Ebenstein 279

Chapter 10 Cells and Membranes Kuo-Kang Liu Kai-Tak Wan 325

Chapter 11 Conclusions and Outlook Michelle L. Oyen 351

Index 357

Editorial Reviews

"Michelle Oyen has done a superb job compiling experts in the field of nanoindentation. This book spans a wide variety of topics ranging from the fundamental theory and instrumentation of nanoindentation to its application in biological materials including soft tissues, mineralized tissues, and cell structures. This book is an excellent resource for students and researchers alike."
—Professor Lisa Pruitt, University of California, Berkeley, USA

From the Publisher