Gasotransmitters

by Rui Wang (Editor)

Overview

Gasotransmitters are gas molecules produced endogenously in prokaryotic and eukaryotic cells for signalling purposes. This book provides, for the first time, a comprehensive description and systematic look at all gasotransmitters, established or proposed, since their detection in 2002. The content and scope covers the production, metabolism, and signalling roles of gasotransmitters. Conceptual advances, scientific discoveries and newly developed techniques described in this book influence our understanding of fundamental molecular and cellular events in biology and medicine.

This book serves as the state-of-the-art book for undergraduate and graduate students as well as post-doctoral fellows in biomedical disciplines and toxicologists studying the toxic mechanisms of gasotransmitters in the environment. It will also be welcomed by researchers in university and research institutes, government agencies, pharmaceutical and medical instrument industry, and clinical practice.

Product Details

ISBN-13:	9781788014809
Publisher:	Royal Society of Chemistry
Publication date:	06/27/2018
Series:	ISSN
Sold by:	Barnes & Noble
Format:	eBook
Pages:	301
File size:	2 MB

About the Author

Dr. Rui Wang is the Vice-President Research and a professor of Biology of Laurentian University in Canada. He served as Vice President of Research, Economic Development and Innovation at Lakehead University in Canada until 2015. Prior to that, Dr. Wang was a Professor of Physiology and leader of both the Cardiovascular Research Group and the Cardiovascular and Respiratory Network at the University of Saskatchewan, and an Assistant Professor at the Université de Montréal. Dr. Wang was trained in China as a medical doctor, and later received his PhD degree in 1990 from the University of Alberta. He was the first to conceptualize the gasotransmitter family in 2002. His achievements have been recognized with numerous national and international honors and awards, including election to fellow of the Canadian Academy of Health Sciences in 2010 and recipient of the Pfizer Senior Scientist Award from Canadian Society of Pharmacology and Therapeutics in 2008. Dr. Wang has published about 266 peer-reviewed papers in leading scientific journals, including Science and Cell. His publication on H2S biology and medicine has received the highest citations in this field in the world.
Dr Rui Wang has been Vice-President of Research of Laurentian University since January of 2015. From 2004 to 2014, Dr Wang served as the Vice President of Research firstly, and then as Vice President of Research, Economic Development and Innovation at Lakehead University. Dr Wang came to Lakehead from the University of Saskatchewan, where he was a Professor of Physiology and leader of both the Cardiovascular Research Group and the Cardiovascular and Respiratory Network. Prior to that, Dr Wang was a Principal Investigator from 1995 to 2000 at the Mount Desert Island Biological Laboratory in Maine, USA, and an Assistant Professor at the Université de Montréal from 1993 to 1997. Dr Wang was trained in China as a medical doctor, and later received his PhD degree in 1990 from the University of Alberta. Dr Wang is an international leader in the study of the metabolism and physiological functions of a group of small molecules of gas, known as gasotransmitters

Table of Contents

Overview of Gasotransmitters and the Related Signaling Network; Production of NO – The L-arginine/NOS/NO System; Production of H2S – The L-cysteine/CSE-CBS-MST/H2S System; HO-1-derived CO is a Regulator of Vascular Function and Metabolic Syndrome; Production and Signalling Functions of Ammonia in Mammalian Cells; The Interaction of NO and H2S Signaling Systems in Biology and Medicine; Signaling by CO: Molecular and Cellular Functions; Production and Signalling of Methane; Gasotransmitters in Plants