Table of Contents
Preface xxiii
Foreword xxv
List of Contributors xxvii
Section I Epilepsy: Epidemiology, Diagnostic Evaluation and Co-Morbidities 1
1 Introduction and Epidemiology 3Joseph I. Sirven and Gregory D. Cascino
2 Classification of Seizures and the Epilepsies 11Elaine C. Wirrell
3 Etiology and Pathology of Epilepsy 23Katherine C. Nickels and Katherine Noe
4 Genetics of Epilepsy 37Anthony L. Fine, Lily C. Wong-Kisiel and Raj D. Sheth
5 Burden of Epilepsy 63J. Layne Moore, Amy Z. Crepeau and Gregory D. Cascino
6 EEG and Epilepsy 77Anteneh M. Feyissa, Gregory A. Worrell and Terrence D. Lagerlund
7 Neuroimaging in Epilepsy 99Benjamin H. Brinkmann, Elson L. So, Robert E. Watson and Amy L. Kotsenas
8 The Evaluation of Nonepileptic Paroxysmal Events 117Sara Dawit and Joseph F. Drazkowski
9 Sleep, Sleep Disorders, and Epilepsy 133Diego Z. Carvalho, J. Layne Moore and Erik K. St. Louis
Epilepsy Journey: Identification of a Genetic Etiology for Epilepsy 147Anthony L. Fine, Lily C. Wong-Kisiel and Raj D. Sheth
Epilepsy Journey 2: Evaluation of Spells in Adults 153David B. Burkholder
Epilepsy Journey 3: The Pediatric Patient with Spells: Recommendations for Evaluation 157Katherine C. Nickels and Elaine C. Wirrell
Epilepsy Journey 4: Transitioning from Pediatric to Adult Epilepsy Clinic 165Gregory D. Cascino, Katherine C. Nickels and Elaine C. Wirrell
Section II Epilepsy: Treatment of Epilepsy: Non-Surgical Therapy 169
10 First Seizure 171Scott Spritzer and Omar Danoun
11 Antiseizure Medication Therapy 179Kiran M. Kanth, Sarah Clark and Jeffrey W. Britton
12 Epilepsy in Women 217Katherine Noe
13 Treating Children with Epilepsy: Antiepileptic Medications (AEDs) 229Raj D. Sheth
14 Dietary Therapy in Epilepsy 239Katherine C. Nickels and Elaine C. Wirrell
15 Autoimmune Epilepsy Disorders 249Jeffrey W. Britton, Eoin P. Flanagan, Andrew McKeon and Sean J. Pittock
16 Discontinuation of Antiseizure Medication 275Jamal F. Khattak and Jeffrey W. Britton
17 Investigational Therapy and Drug Approval Process within the US and Cannabidiol 287Gregory Sprout, Joseph I. Sirven and Gregory D. Cascino
18 Devices to Monitor and Track Your Epilepsy 301Nicholas M. Gregg and Amy Z. Crepeau
Epilepsy Journey 5: Seizure Emergencies (Include status Epilepticus, Fires, Norse, Seizure First Aid, and Seizure Clusters) 313Anteneh M. Feyissa, Matthew T. Hoerth and Eric T. Payne
Epilepsy Journey 6: The First seizure How to Evaluate: Pediatric 315Korwyn Williams
Epilepsy Journey 7: The First Seizure How to Evaluate: Adult 317Paul M. Magtibay and Joseph I. Sirven
Epilepsy Journey 8: Treating Epilepsy Second Seizure and beyond: How to Choose a Drug An Algorithm 321Amy Z. Crepeau
Epilepsy Journey 9: Treating Status Epilepticus: An Algorithm 325Sara E. Hocker and Eric T. Payne
Epilepsy Journey 10: Withdrawal of ASDs in Adults: An Algorithm 331Sarah A. Merrill, Kent R. Richter and Joseph I. Sirven
Epilepsy Journey 11: Withdrawal of ASDs in Seizure-Free Patients Children: The PediatricNeurologist’s Perspective 335Elaine C. Wirrell
Epilepsy Journey 12: Withdrawing ASDs in Adults after Epilepsy Surgery 339Christian Rosenow, Luca Farrugia, Andrew Pines and Joseph I. Sirven
Epilepsy Journey 13: The Pregnant Patient with Epilepsy: An Algorithm 343Katherine Noe
Section III Epilepsy: Treatment of Epilepsy: Surgical Management 345
19 Pre-surgical Evaluation 347David B. Burkholder, Anthony L. Ritaccio and Cheolsu Shin
20 Minimally Invasive Epilepsy Surgery 367Sanjeet S. Grewal, Robert E. Wharen Jr. and William O. Tatum
21 Intracranial EEG Monitoring 381Jamie J. Van Gompel, Katherine Noe and Richard S. Zimmerman
22 Surgical Strategies (Include Cortical Resection, Lesionectomy, Cortical Stimulation and Functional Mapping, Hemispherotomy) 401Angela Bohnen, W. Richard Marsh, Alfredo Quinones-Hinojosa and Kaisorn L. Chaichana
23 Corpus Callosotomy 413Elaine C. Wirrell, Lily C. Wong-Kisiel and Kai J. Miller
24 Neuromodulation for Epilepsy 431Brian N. Lundstrom, Robert E. Wharen, Jr and William O. Tatum
25 Emerging Treatments for Epilepsy 441Gregory A. Worrell, Benjamin H. Brinkmann, Brian N. Lundstrom and Matt Stead
26 Seizure Forecasting in Epilepsy: From Computation to Clinical Practice 451Benjamin H. Brinkmann, Nicholas M. Gregg and Gregory A. Worrell
Epilepsy Journey 14: The Drug-Resistant Patient: Pre-surgical Evaluation and Surgery-Approach to the "Skip" Candidate 463Anteneh M. Feyissa and David B. Burkholder
Epilepsy Journey 15: The Drug-Resistant Patient and Discordant Pre-surgical Evaluation 469Lily C. Wong-Kisiel, Elson L. So and Richard S. Zimmerman
Epilepsy Journey 16: The Drug-Resistant Patient who is not a Candidate for Resective Surgery: An Approach to Neuromodulation 477Anthony L. Ritaccio and William O. Tatum
Epilepsy Journey 17: Epilepsy Surgery in Pediatric Patients 483Raj D. Sheth, Kai J. Miller and Elaine C. Wirrell
References 489
Index 491