| Julia Roberts | Captain Kate Hazeltine |
| Emma Roberts | Grace |
| Anne Hathaway | Liz |
| Jessica Alba | Morley Clarkson |
| Jessica Biel | Kara Monahan |
| Jennifer Garner | Julia Fitzpatrick |
| Shirley MacLaine | Estelle |
| Kathy Bates | Susan |
| Bradley Cooper | Holden |
| Ashton Kutcher | Reed Bennett |
| Topher Grace | Jason |
| Eric Dane | Sean Jackson |
| Patrick Dempsey | Dr. Harrison Copeland |
| George Lopez | Alphonso |
| Queen Latifah | Paula Thomas |
| Hector Elizondo | Edgar |
| Jamie Foxx | Actor |
| Taylor Lautner | Willy |
| Taylor Swift | Felicia |
| Bryce Robinson | Edison |
| Matt Walker | Greg Gilkins |
| Larry Miller | Oversized Baggage Agent |
| Beth Kennedy | Mrs. Claudia Smart |
| Katherine La Nasa | Pamela Copeland |
| Kristen Schaal | Ms. Gilroy |
| Erin Matthews | Flight Attendant |
| Christine Lakin | Heather |
| Lauren Reeder | Hotel Clerk Michelle |
| Joey Sorge | Bistro Garden Maitre'd Amos |
| Julia Springer | Olivia Copeland |
| Alec Nemser | Charlie |
| Kathleen Marshall | Nikki |
| Rick Batalla | Michael |
| Anna Kulinova | Bulgarian Girl |
| Cassie Rowell | Coffee Barista |
| Faline England | Flower Shop Customer #1 |
| James F. McCann | Flower Shop Customer #2 |
| Shea Curry | Friend Elise |
| Alexis Peters | Friend Dana |
| Wedil David | Rani's Mom Rehka |
| Natalie Timmermans | Indian Bride |
| Jennifer Leigh Warren | Party Singer |
| Scott Crumly | Indian Restaurant Valet |
| Jonathan Morgan Heit | Tough Franklin |
| Megan Suri | Rani |
| Brooklyn Proulx | Madison |
| Karolinah Villarreal | Gwen |
| Angelo Salvatore Restaino | Alex's Friend Gideon |
| Scott Marshall | Mr. Schwabbe |
| Kelly Flynn | Referee |
| Sam Marshall | Soccer Son |
| Mandy Medlin | Teacher |
| Larrs Jackson | Chauffer Redmond |
| Cleo King | TAS Supervisor Daisy Bell |
| Corena Chase | TAS Security Officer |
| Justin Michael Duval | TAS Security Guard |
| Heidi Brucker | Southwest Gate Agent |
| Lily Marshall-Fricker | Lily |
| Kamilla Bjorlin | Sherry Donaldson |
| Anna Aimee White | Weather Girl |
| Stefanie Sherk | Stage Manager |
| Marty Nadler | Camerman #1 |
| Scott Sener | Camerman #2 |
| Colin Owens | Male Anchor |
| Calvin Jung | Simon |
| Serena Poon | Chinese Vendor |
| Kazumi Nakamura | Japanese Vendor |
| Gwenda Perez | Spanish Vendor |
| Kiko Kiko | Dodger Grandmother |
| Joseph Leo Bwarie | Mailroom Danny |
| Robert Belushi | Mailroom Ted |
| Jaclyn Miller | ACM Receptionist |
| Joe Smith | ACM Restaurant Waiter |
| Katie Joy | ACM Outdoor Café Waitress |
| Lisa Roberts Gillan | Young Nurse |
| Barbara Marshall | Head Nurse |
| Stephanie Fabian | Candy Striper |
| Sandra Taylor | Beach Girl Candy |
| Sarah Lilly | Lady With Dog |
| Tony Scruggs | Beverly Wilshire Waiter |
| Roberta Valderrama | Angry Girlfriend |
| Cyrus Alexander | Cisco the Cheater |
| Peter Allen Vogt | Cupid |
| Paul Vogt | Shouting Sheldon |
| Bonnie Aarons | Strange Lady |
| Adreanna Gonzalez | Cemetery Ticket Vendor |
| Matt Merchant | Loud Guy |
| Lisa Valenzuela | Loud Lady |
| Howard Storm | Louder Guy |
| Jennifer Amy | Bistro Gardens Waitress |
| Rance Howard | Bistro Garden Diner |
| Travina Springer | Sign Language Interpreter |
| Tracy Reiner | French Photographer |
| Hannah Storm | ESPN Hannah Storm |
| Mike Golic | ESPN Radio Announcer |
| Mike Greenberg | ESPN Radio Announcer |
| Paul Williams | Romeo Midnight |
Technical Credits
| Garry Marshall | Director |
| Deborah Aquila | Casting |
| Albert Brenner | Production Designer |
| Samuel J. Brown | Executive Producer |
| John Debney | Score Composer |
| Michael Disco | Executive Producer |
| Toby Emmerich | Executive Producer |
| Katherine Fugate | Original Story,Screenwriter |
| Adrian H. Gorton | Art Director |
| Bruce Green | Editor |
| Jeremy Hays | Special Effects Supervisor |
| Gary Jones | Costumes/Costume Designer |
| Mike Karz | Producer |
| Abby Kohn | Original Story |
| Mark Mangini | Sound/Sound Designer |
| Masako Masuda | Set Decoration/Design |
| Charles Minsky | Cinematographer |
| Diana Pokorny | Executive Producer |
| Wayne Rice | Producer |
| Josie Rosen | Executive Producer |
| Marc Silverstein | Original Story |
| David H. Venghaus | Asst. Director |
| Bruce K. West | Set Decoration/Design |
| Tricia Wood | Casting |