Comprehensive Bioactive Natural Products (Quality Control & Standardization)

by V.K. GUPTA, S.C. TANEJA

Overview

Herbal drugs have a prolonged history of frequent use and documentation in texts of established systems of medicine indigenous to a particular country. There is a great demand for these medicines in the developed as well as developing countries because of their wide biological activities, higher safety margin than the synthetic drugs and lesser costs. Since these medicines are prepared from materials of plant origin they are prone to, deterioration and variation in composition. Extremely limited knowledge about the ingredients in the herbal drug formulations and their effects in humans, the lack of stringent quality control and the heterogeneous nature of these preparations all necessitate the continuous monitoring of the safety of the herbal products. The World Health Organization has recognized the importance of traditional medicine and has created strategies, guidelines and standards for botanical medicines. It is necessary to develop methods for rapid precise and accurate identification and estimation of active constituents in order to bring out consistency of important constituents in the formulations. In present volume Quality Control and Standardization of the book series Compendium of Bioactive natural Products an attempt has been made to cover the recent progress in standardization of the herbal/ traditional drugs and strategies adopted for quality assurance. The book is not only an excellent source material for the scientists and teachers but also for research workers working on different aspects of bioactive natural products and comprises fourteen original research papers/review articles, and we believe, it shall receive an overwhelming response from our esteemed readers hailing from various corners across the globe.

Product Details

ISBN-13:	9781626993495
Publisher:	Arts & Science Academic Publishing
Publication date:	06/30/2010
Sold by:	Barnes & Noble
Format:	eBook
Pages:	344
File size:	6 MB

About the Author

Dr. Vijay Kumar Gupta, Ph.D., FLS, London (born 1953-) Deputy Director & Head, Animal House, Indian Institute of Integrative Medicine (CSIR), Jammu, India. He did his M.Sc. (1975) and Ph.D. (1979) in Zoology both from University of Jammu, Jammu-India. His research capabilities are substantiated by his excellent work on histopathology, ecology and reproductive biology of fishes, turtles, birds and mammals, which has already got recognition in India and abroad. Dr. Gupta has to his credit more than 75 scientific publications and review articles which have appeared in internationally recognized Indian and foreign journals. Founder fellow, life member and office bearer of many national societies, academies and associations. He has successfully completed a number of research/consultancy projects funded by various governments, private and multinational agencies. His current areas of interest are histopathology, toxicology, pre-clinical safety pharmacology and reproductive efficacy studies of laboratory animals. He is also Editor-in-chief of the books 1) Utilisation and Management of Medicinal Plants 2) Medicinal Plants: Phytochemistry, Pharmacology and Therapeutics 3) Perspectives in Animal Ecology and Reproduction (Vols.1-6). The Editor-in-chief of the American Biographical Institute, USA, has appointed him as Consulting Editor of The Contemporary Who’s Who. Dr. Gupta also appointed as Nominee for the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA, Govt. of India). Recently the Linnaean Society of London, U.K. has awarded fellowship to him in November 2009 in recognition of his contribution towards the cultivation of knowledge in Science of Natural History.



Dr. Subhash Chandra Taneja (born 1950-) obtained his masters degree in Organic Chemistry in 1971 and thereafter completed Ph.D. in Birla Institute of Technology & Science, Pilani, India in 1975 under the guidance of Prof.H.P. Tiwari. He is scientist of eminence and presently working as Scientist ‘G’, Indian Institute of Integrative Medicine (CSIR), Jammu. Dr. Taneja has over 100 publications in international journals, two book chapters and two review articles, 38 patents of which 14 are USP. He has also visited Institute of Organic Chemistry, Warsaw, Poland (1989-1990) under CSIR Scientist Exchange Programme. His areas of interest are chemistry and bioactivities of medicinal plants and generation of semi-synthetic libraries based on natural product scaffolds; design and synthesis of bioactive lead molecules in the area of inflammation, oncology, infectious diseases, immunomodulation; exploitation of microbial biodiversity for the identification newer sources of biocatalysts e.g. lipases, esterases, glucosidases, nitrilases, oxido-reductases etc. and development of new throughput screening techniques; synthesis and kinetic resolution of important dugs/intermediates using chemo-enzymatic methods; development of green methodologies for the synthesis of mono terpenes and perfumery molecules; development of new glycosylation methodologies; C- and O-glycosylation techniques; new synthetic protection-deprotection methodologies for carbohydrates, and their conversion to bioactive molecules and organic synthesis of natural products and bioactive molecules.