Clinical Neurology and Neuroanatomy: A Localization-Based Approach, Second Edition
336
Clinical Neurology and Neuroanatomy: A Localization-Based Approach, Second Edition
336eBook
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Overview
A Doody's Core Title for 2023!
An Engagingly Written Text That Bridges the Gap Between Neuroanatomy and Clinical Neurology
Clinical Neurology and Neuroanatomy provides a clear, logical discussion of the relationship between neuroanatomy, clinical localization, and the diagnosis and treatment of neurologic disease. Written in a concise, conversational style, this unique text offers a valuable overview of fundamental neuroanatomy and the clinical localization principles necessary to diagnose and treat patients with neurologic diseases and disorders.
The text is divided into main sections. Part I teaches the neuroanatomy essential for clinical localization and demonstrates how to apply this knowledge to clinical reasoning in developing a differential diagnosis for common neurologic symptoms including weakness, sensory changes, visual loss, ataxia, diplopia, anisocoria, and dizziness. A detailed overview of the neurologic examination and a primer on interpretation of neurodiagnostic tests with a focus on neuroimaging and CSF analysis is also included.
Part II provides an up-to-date synthesis of the diagnosis and treatment of neurologic diseases including epilepsy, stroke, neurologic infections, demyelinating diseases, dementia, movement disorders, neurologic complications of cancer and its treatment, and conditions of the peripheral nervous system. More than 50 radiologic images of common and rare neurologic conditions and over 30 tables summarizing key aspects of various conditions and their treatment are featured.
Clinical Neurology and Neuroanatomy is an ideal companion for students on their neurology rotation, neurology residents, and any healthcare practitioner looking for a quick, clear, up-to-date resource in neurology.
NEW IN THE UPDATED AND EXPANDED SECOND EDITION
- 26 new full-color neuroanatomy illustrations plus numerous high-resolution MRI and CTI scans
- New sections on multiple cranial neuropathies, vertical diplopia, basal ganglia circuitry, functional movement disorders, neurologic complications of immune checkpoint inhibitors and CAR T-cell therapy, and antibody-mediated neurologic diseases
- Updated and expanded tables including new treatments for seizures, multiple sclerosis, and migraine; recently described autoantibody-mediated conditions; and revised classification of brain tumors
- Updated chapter on strokes reviews the latest clinical trial data on acute stroke treatments, use of dual antiplatelet regimens, and PFO closure
Product Details
| ISBN-13: | 9781260453379 |
|---|---|
| Publisher: | McGraw Hill LLC |
| Publication date: | 07/22/2022 |
| Sold by: | Barnes & Noble |
| Format: | eBook |
| Pages: | 336 |
| Sales rank: | 721,818 |
| File size: | 44 MB |
| Note: | This product may take a few minutes to download. |
About the Author
Aaron Berkowitz, MD, PhD, is Director of Global Health and Professor of Clinical Science at the brand-new KaiserPermanente Bernard J. Tyson School of Medicine in Pasadena, California, where heis leading development of its neurology curriculum.
Table of Contents
Foreword ix
Preface to the First Edition xi
Preface to the Second Edition xiii
Acknowledgments xv
Part 1 Neuroanatomy & Neuroanatomic Localization 1
1 Diagnostic Reasoning in Neurology & the Neurologic History & Examination 1
Localization in Neurologic Diagnosis: Determining Where the Problem is 1
Time Course in Neurologic Diagnosis: Determining What the Problem is 2
Associated Symptoms & Signs in Neurologic Diagnosis 3
Introduction to the Neurologic Examination 3
2 Introduction to Neuroimaging & Cerebrospinal Fluid Analysis 11
Neuroimaging in Clinical Practice 11
Overview of Neuroimaging Interpretation 12
Interpretation of Brain CT 12
Interpretation of Brain MRI 13
Contrast-Enhanced Neuroimaging 18
Vascular Imaging 19
Nuclear Medicine Studies: Positron Emission Tomography & Single Photon Emission Computed Tomography 21
Neuroimaging of the Spine 21
Cerebrospinal Fluid Analysis 21
3 Overview of the Anatomy of the Nervous System 25
Central Nervous System (CNS) & Peripheral Nervous System (PNS) 25
Hemispheres & Lobes of the Brain 25
Gray Matter & White Matter of the Brain & Spinal Cord 26
The Meninges: Coverings of the Brain & Spinal Cord 26
The Cerebral Venous Sinuses 29
The Ventricular System & Cerebrospinal Fluid Flow 29
4 The Motor and Somatosensory Pathways & Approach to Weakness and Sensory Loss 33
The Corticospinal Tracts 33
The Corticobulbar Tracts 35
Somatosensory Pathways for the Body 36
Localization of Motor & Sensory Deficits 37
5 The Spinal Cord & Approach to Myelopathy 41
Overview of Spinal Cord Anatomy 41
Lamination of the Long Tracts in the Spinal Cord 41
Spinal Cord Syndromes 42
Spinal Cord Pathways for Bowel & Bladder Control 47
Causes of Myelopathy 47
6 The Visual Pathway & Approach to Visual Loss 49
Anatomy of the Visual Pathway 49
Approach to Visual Loss 51
Disorders of Visual Cognition 54
7 The Cerebral Hemispheres & Vascular Syndromes 55
Cortical Regions 55
Subcortical Structures: Thalamus & Basal Ganglia 57
Arterial Supply of the Cerebral Hemispheres 63
Clinical Syndromes Associated With Cerebral Vascular Territories 65
8 The Cerebellum & Approach to Ataxia 73
Anatomy & Function of the Cerebellum 73
Arterial Supply of the Cerebellum 77
Approach to Ataxia 77
9 The Brainstem & Cranial Nerves 81
Overview of Brainstem Anatomy 81
Clinical Applications of Brainstem Anatomy 83
10 Pupillary Control & Approach to Anisocoria Cranial Nerves 2 & 3 91
Pupillary Constriction: The Parasympathetic Pathway 91
Pupillary Dilation: The Sympathetic Pathway 93
Approach to Anisocoria and Other Pupillary Abnormalities 95
11 Extraocular Movements & Approach to Diplopia Cranial Nerves 3, 4, & 6 99
Extraocular Movements I: Muscles & Their Innervation 99
Extraocular Movements II: Cranial Nerves 3, 4, & 6 100
Extraocular Movements III: Supranuclear Control of Horizontal & Vertical Gaze 105
Approach to Diplopia 112
12 The Auditory and Vestibular Pathways & Approach to Hearing Loss and Dizziness/Vertigo Cranial Nerve 8 117
The Auditory System 117
Approach to Hearing Loss 117
The Vestibular System 119
Approach to Dizziness & Vertigo 122
13 Facial Sensory and Motor Pathways & Approach to Facial Sensory and Motor Deficits Cranial Nerves 5 & 7 129
Trigeminal Nerve (Cranial Nerve 5) 129
Facial Nerve (Cranial Nerve 7) 132
14 Cranial Nerves 1, 9, 10, 11, & 12 137
Cranial Nerve 1 (Olfactory Nerve) 137
Cranial Nerve 9 (Glossopharyngeal) & Cranial Nerve 10 (Vagus) 137
Cranial Nerve 11 (Spinal Accessory) 138
Cranial Nerve 12 (Hypoglossal) 138
15 The Peripheral Nervous System & Introduction to Electromyography/Nerve Conduction Studies 141
Introduction to Anatomy & Diseases of the Peripheral Nervous System 141
Anatomy & Diseases of Nerve Roots: Radiculopathy 142
Diseases of Dorsal Root Ganglia: Ganglionopathy (Sensory Neuronopathy) 146
Diseases of the Brachial or Lumbosacral Plexus: Plexopathy 146
Diseases of Peripheral Nerves 146
Introduction to EMG & Nerve Conduction Studies 148
16 Radiculopathy, Plexopathy, & Mononeuropathies of the Upper Extremity 153
Neuroanatomy of the Upper Extremity 153
Cervical Radiculopathy & Cervical Stenosis 157
Brachial Plexopathy 159
Mononeuropathies of the Upper Extremity 160
17 Radiculopathy, Plexopathy, & Mononeuropathies of the Lower Extremity 169
Neuroanatomy of the Lower Extremity 169
Lumbosacral Radiculopathy & Lumbar Canal Stenosis 171
Lumbosacral Plexopathy 175
Mononeuropathies of the Lower Extremity 176
Approach to Foot Drop 178
Part II Diseases of the Nervous System 179
18 Seizures & Epilepsy 179
Definitions & Causes of Seizures & Epilepsy 179
Evaluation of Patients With Seizures 180
Clinical Features of Seizures 181
Electroencephalography (EEG) in the Evaluation of Seizures 182
Evaluation & Management of Patients After a First Seizure 183
Outpatient Management of Epilepsy 185
Special Scenarios in the Management of Seizures & Epilepsy 189
Status Epilepticus 191
19 Vascular Diseases of the Brain & Spinal Cord 195
Overview of Ischemic Stroke & Intracerebral Hemorrhage 195
Ischemic Stroke 196
Intracerebral Hemorrhage 210
Central Nervous System Vascular Malformations 213
Subarachnoid Hemorrhage 215
Intraventricular Hemorrhage 218
Subdural Hematoma 218
Epidural Hematoma 218
Cerebral Venous Sinus Thrombosis & Cortical Vein Thrombosis 219
Other Cerebrovascular Disorders 221
Vascular Disease of the Spinal Cord 221
20 Infectious Diseases of the Nervous System 227
Meningitis 227
Viral Encephalitis 233
Focal Infectious Brain Lesions 235
Infections of the Spine 239
Infections of Nerve Roots 241
Infectious Peripheral Neuropathies 241
Infection at the Neuromuscular Junction: Botulism 241
Infectious Myositis 242
Neurologic Manifestations of HIV 242
21 Demyelinating Diseases of the Central Nervous System 245
Multiple Sclerosis 245
Neuromyelitis Optica Spectrum Disorder 250
Myelin Oligodendrocyte Glycoprotein (Mog) Antibody Disease 251
Acute Disseminated Encephalomyelitis 252
Optic Neuritis 252
Transverse Myelitis 253
22 Delirium, Dementia, & Rapidly Progressive Dementia 255
Approach to Altered Cognition 255
Delirium 255
Dementia 257
Rapidly Progressive Dementia 263
23 Movement Disorders 267
Introduction to Movement Disorders 267
Tremor 269
Myoclonus 270
Chorea 271
Dystonia 273
Tics, Tourette's Syndrome, & Sterotypies 274
Parkinsonism, Parkinson's Disease, & Parkinson-Plus Syndromes 274
Functional Movement Disorders 281
Other Movement Disorders 281
24 Neoplastic and Paraneoplastic Disorders of the Nervous System & Neurologic Complications of Chemotherapy and Radiation Therapy 285
Intracranial Tumors 285
Tumors of the Spine 291
Tumors of the Cranial Nerves 292
Tumors of the Peripheral Nervous System 292
Neurocutaneous Syndromes & Associated Nervous System Neoplasms 293
Neurotoxicity of Chemotherapy & Radiation Therapy 293
Paraneoplastic/Antibody-Mediated Syndromes of the Nervous System 296
Cerebrovascular Complications of Cancer 299
25 Disorders of Intracranial Pressure 301
Increased Intracranial Pressure (Intracranial Hypertension) 301
Decreased Intracranial Pressure (Intracranial Hypotension) 305
26 Headache 307
Approach to Headache 307
Secondary Causes of Headache 307
Primary Headache Disorders 308
Other Causes of Headache 312
27 Peripheral Neuropathy 315
Classification & Differential Diagnosis of Peripheral Polyneuropathy 315
Acute Polyneuropathy 317
Chronic Polyneuropathy 319
28 Motor Neuron Disease 325
Overview of Motor Neuron Disease 325
Amyotrophic Lateral Sclerosis (ALS) & Its Variants 325
Spinal Muscular Atrophy (SMA) & Spinal Bulbar Muscular Atrophy (Kennedy's Disease) 327
29 Disorders of the Neuromuscular Junction 329
Myasthenia Gravis 329
Congenital Myasthenic Syndromes & Neonatal Myasthenia Gravis 332
Lambert-Eaton Myasthenic Syndrome 332
30 Diseases of Muscle 335
Causes of Muscle Disease 335
Clinical Features of Muscle Disease 335
Laboratory Testing in Muscle Disease 336
Inflammatory Myopathies 336
Muscular Dystrophies 337
Distal Myopathies (Distal Muscular Dystrophies) 339
Congenital Muscular Dystrophies & Congenital Myopathies 340
Metabolic Myopathies 340
Mitochondrial Myopathies 341
Hyperkalemic & Hypokalemic Periodic Paralysis 341
Muscle Disease Due to Systemic Diseases & Medications 343
31 Leukodystrophies & Mitochondrial Diseases 345
Leukodystrophies 345
Mitochondrial Diseases 345
Index 349