Table of Contents
Contents to Volume 1 List of Contributors xi
Preface xvii
Part I Chemistries 1
1 A Brief Introduction to Traditional Bioconjugate Chemisrty 3W. Russ Algar
2 (3+2)-Doplar Cycloadditions in Bioconjugation 37Jason E. Hein
3 Diels-Adler and Inverse Diels-Adler Reactions 67Roberto J. Brea and Neal K. Devaraj
4 The Straudinger Ligation 97Olaia Nieto-Garcia, Marcie B. Jaffee, Michaela Muhlberg, and Christian P.R. Hackenberger
5 Thiol-Ene Chemistry 117Neil B. Cramer and Christopher N. Bowman
6 Ligand-Directed Tosyl and Acyl Imidazole Chemisrty 147Kazuya Matsuo and Itaru Hamachi
7 Bioorthogonal Labeling of Cellular Proteins by Enzymatic and Related Mechanisms 165Scott A. Walper, Kendrick B. Turner, and Igor L. Medintz
8 Metal-Mediated Bioconjugation 231Justin M. Chalker
Contents to Volume 2
List of Contributors xiii
Preface xix
Part II applications 271
9 Protein and Anitbody Labeling 273Angela M. Mariani and Kim E. Sapsford
10 Activity-Based Protein Profiling 305Elaine V. Wolf and Steven H.L. Verhelst
11 Nucleic Acid Labeling, Ligation and Modicfication 335Afah H. El-Sagheer and Tom Brown
12 Chemoselective Reactions for Glycan Labeling 363Janet E. McCombs and Jennifer J. Kholer
13 Chemoselective Attachment of Lipids to Proteins 391Christian F. W. Becker
14 In Vivo Applications of Bioorthogonal Chemistries 417Chelsea G. Gordon and Carolyn R. Bertozzi
15 Immobilization of Biomolecular Probes for Arrays and Assays: Critical Aspects of Biointerfaces 459Stella H. North and Chris Rowe Taitt
16 Chemical Ligations in the Design of Hydrogel Materials 497Scott H. Medina and Joel P. Schneider
17 Nanoparticle Bioconjugates: Materials that Benefit from Chemoselective and Bioorthogonal Ligation Chemistires 543Melissa Massey and W. Russ Algar
18 Applications of Engineered Viral Nanoparticles in Materials and Medicine 631Michael D. Glidden II, John F. Edelbrock, Amy M. Wen, Sourabh Shukla, Yingfang Ma, Roger H. French, Jonathan K. Pokorski, and Nicole F. Steinmetz
Index 711