Changing Connectomes: Evolution, Development, and Dynamics in Network Neuroscience

by Marcus Kaiser

Overview

An up-to-date overview of the field of connectomics, introducing concepts and mechanisms underlying brain network change at different stages.

The human brain undergoes massive changes during its development, from early childhood and the teenage years to adulthood and old age. Across a wide range of species, from C. elegans and fruit flies to mice, monkeys, and humans, information about brain connectivity (connectomes) at different stages is now becoming available. New approaches in network neuroscience can be used to analyze the topological, spatial, and dynamical organization of such connectomes. In Changing Connectomes, Marcus Kaiser provides an up-to-date overview of the field of connectomics and introduces concepts and mechanisms underlying brain network changes during evolution and development.

Product Details

ISBN-13:	9780262360814
Publisher:	MIT Press
Publication date:	09/08/2020
Sold by:	Penguin Random House Publisher Services
Format:	eBook
Pages:	248
File size:	4 MB

About the Author

Marcus Kaiser is Professor of Neuroinformatics in the School of Computing at Newcastle University and Visiting Professor at Shanghai Jiao Tong University. He is a Fellow of the Royal Society of Biology and is Chair of Neuroinformatics UK.

Table of Contents

Preface
1. Introduction
Part I. Connectome Structure
2. Features of Complex Networks
3. Evolution of Neural Systems
4. Organization of Neural Systems
Part II. Connectome Maturation
5. Brain Development
6. Layer Formation
7. Axonal Growth
8. Formation of Hubs
9. Module Formation
10. Cortical Folding
Part III. Connectome Changes
11. Development and Ageing
12. Neurodevelopmental Disorders
13. Neurodegenerative Disorders
14. Recovery from Injury
15. Brain Stimulation Effects
Glossary
References

Editorial Reviews

"A central focus of contemporary connectomics is on patterns of change — capturing how connectomes grow, mature, degenerate, evolve, adapt and reconfigure. This important book provides a comprehensive account of how these changes unfold, and how they relate to brain dynamics, cognition and behavior."
– Olaf Sporns, Distinguished Professor, Indiana University; author of Networks of the Brain and Discovering the Human Connectome

"From the wiring diagram of the worm nervous system through to the gamechanging potential of big data and AI, the author clearly lays out basic principles and thoughtfully guides the reader through cuttingedge discoveries and future applications of the exploding science of brain connectomics."
– Heidi JohansenBerg, University of Oxford; author of Diffusion MRI

From the Publisher