Celiac Disease (Updated 4th Edition): A Hidden Epidemic
From Dr. Peter H. R. Green, internationally renowned expert on celiac disease and director of the Celiac Disease Center at Columbia University, and medical author Rory Jones, an updated fourth edition of the definitive book on celiac disease, one of the most underdiagnosed autoimmune diseases in the U.S.  

Celiac Disease: A Hidden Epidemic is an indispensable guidebook for anyone with celiac disease as well as for those with gluten intolerance or food sensitivities on a gluten-free diet. Since the last edition in 2016, scientific advances have changed what we know about the disease, how it is diagnosed and treated, and the long-term effect of a gluten-free diet on the brain and body.

Celiac disease is a hereditary autoimmune condition that damages the lining of the small intestine so that it cannot properly absorb food. Without essential nutrients, the entire body begins to suffer. The disease is triggered by gluten, a protein found in wheat, rye, and barley. The only “cure” for the disease is a life-long gluten-free diet. The disease affects nearly 1 in every 100 people in the United States—50 percent of whom remain undiagnosed and untreated. Although the primary target of injury is the small intestine, CD can and often does affect the entire body. Complications from the disease can include infertility, liver disease, osteoporosis, anemia, and other autoimmune diseases (such as Type 1 diabetes and Thyroid disease), neurological conditions, and even cancer.

This updated fourth edition includes the latest information on CD, gluten intolerance, and gluten sensitivity. The important updates cover everything from new testing devices to advances in therapies that may help prevent gluten from entering and/or harming the intestines, to new research on the long-term effect of the gluten-free diet on our minds and bodies. And more!

1100836924
Celiac Disease (Updated 4th Edition): A Hidden Epidemic
From Dr. Peter H. R. Green, internationally renowned expert on celiac disease and director of the Celiac Disease Center at Columbia University, and medical author Rory Jones, an updated fourth edition of the definitive book on celiac disease, one of the most underdiagnosed autoimmune diseases in the U.S.  

Celiac Disease: A Hidden Epidemic is an indispensable guidebook for anyone with celiac disease as well as for those with gluten intolerance or food sensitivities on a gluten-free diet. Since the last edition in 2016, scientific advances have changed what we know about the disease, how it is diagnosed and treated, and the long-term effect of a gluten-free diet on the brain and body.

Celiac disease is a hereditary autoimmune condition that damages the lining of the small intestine so that it cannot properly absorb food. Without essential nutrients, the entire body begins to suffer. The disease is triggered by gluten, a protein found in wheat, rye, and barley. The only “cure” for the disease is a life-long gluten-free diet. The disease affects nearly 1 in every 100 people in the United States—50 percent of whom remain undiagnosed and untreated. Although the primary target of injury is the small intestine, CD can and often does affect the entire body. Complications from the disease can include infertility, liver disease, osteoporosis, anemia, and other autoimmune diseases (such as Type 1 diabetes and Thyroid disease), neurological conditions, and even cancer.

This updated fourth edition includes the latest information on CD, gluten intolerance, and gluten sensitivity. The important updates cover everything from new testing devices to advances in therapies that may help prevent gluten from entering and/or harming the intestines, to new research on the long-term effect of the gluten-free diet on our minds and bodies. And more!

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Celiac Disease (Updated 4th Edition): A Hidden Epidemic

Celiac Disease (Updated 4th Edition): A Hidden Epidemic

by Peter H.R. Green M.D., Rory Jones
Celiac Disease (Updated 4th Edition): A Hidden Epidemic
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Celiac Disease (Updated 4th Edition): A Hidden Epidemic

Celiac Disease (Updated 4th Edition): A Hidden Epidemic

by Peter H.R. Green M.D., Rory Jones

Overview

From Dr. Peter H. R. Green, internationally renowned expert on celiac disease and director of the Celiac Disease Center at Columbia University, and medical author Rory Jones, an updated fourth edition of the definitive book on celiac disease, one of the most underdiagnosed autoimmune diseases in the U.S.  

Celiac Disease: A Hidden Epidemic is an indispensable guidebook for anyone with celiac disease as well as for those with gluten intolerance or food sensitivities on a gluten-free diet. Since the last edition in 2016, scientific advances have changed what we know about the disease, how it is diagnosed and treated, and the long-term effect of a gluten-free diet on the brain and body.

Celiac disease is a hereditary autoimmune condition that damages the lining of the small intestine so that it cannot properly absorb food. Without essential nutrients, the entire body begins to suffer. The disease is triggered by gluten, a protein found in wheat, rye, and barley. The only “cure” for the disease is a life-long gluten-free diet. The disease affects nearly 1 in every 100 people in the United States—50 percent of whom remain undiagnosed and untreated. Although the primary target of injury is the small intestine, CD can and often does affect the entire body. Complications from the disease can include infertility, liver disease, osteoporosis, anemia, and other autoimmune diseases (such as Type 1 diabetes and Thyroid disease), neurological conditions, and even cancer.

This updated fourth edition includes the latest information on CD, gluten intolerance, and gluten sensitivity. The important updates cover everything from new testing devices to advances in therapies that may help prevent gluten from entering and/or harming the intestines, to new research on the long-term effect of the gluten-free diet on our minds and bodies. And more!

Product Details

ISBN-13: 9780063034853
Publisher: HarperCollins
Publication date: 12/01/2020
Pages: 368
Sales rank: 319,720
Product dimensions: 5.30(w) x 7.90(h) x 0.90(d)

About the Author

Peter H.R. Green, M.D., is the director of the Celiac Disease Center at Columbia University. He is the Ivan and Phyllis Seidenberg Professor of Medicine at the College of Physicians and Surgeons, Columbia University and attending physician at the Columbia University Medical Center (New York-Presbyterian Hospital). Celiac disease has been his focus for the last 25 years with equal concentration on patient care and research. He is the co-author of Celiac Disease: A Hidden Epidemic and Gluten Exposed: The Science Behind the Hype and How to Navigate to a Healthy, Symptom-Free Life.


Rory Jones, M.S. is a medical writer and Adjunct Professor of Narrative Medicine at Barnard College of Columbia University. She has done extensive work on health and medical topics, including educational programs for both adults and children. She specializes in ‘translating’ scientific information for a consumer audience. Diagnosed with celiac disease in 1998, she has researched and written about it and the gluten-free diet for medical as well as consumer publications. She is the co-author of Celiac Disease: A Hidden Epidemic and Gluten Exposed: The Science Behind the Hype and How to Navigate to a Healthy, Symptom-Free Life.

Table of Contents

Acknowledgments xix

A Note from the Authors xxi

Introduction: What's Wrong with Me? 1

Part I Is the Food You Eat Eating You? 5

1 Normal Digestion 7

The Gastrointestinal (GI) Tract

Digestion

The Mouth

The Stomach

One-Way Street

The Pancreas

The Liver

The Small Intestine

Absorption

Transport

Gluten: The Problem Protein

The Colon (Large Intestine)

When Normal Goes Pathological

In Summary

2 The Digestive Tract in Flames: Celiac Disease 20

Celiac Disease

What Is Gluten?

What Goes Wrong: The Role of Inflammation

What Is Tissue Transglutaminase (tTG)?

The Intestinal Battlefield

The Digestive Tract in Flames

3 How Does Celiac Disease Affect You? 27

Severe or "Classic"

Atypical Celiac Disease

Silent Celiac Disease

Every Body Reacts Differently

Intestinal Problems

The Manifestations of Malabsorption

Systemic Inflammatory Reactions and Autoimmune Diseases

Malignancies

4 How Do I Know If I Have It? The Diagnosis of Celiac Disease 40

Food Allergy versus Gluten Intolerance versus Food or Non-Celiac Gluten Sensitivity

The Diagnosis

Potential Celiac Disease

Blood Tests

Sensitivity and Specificity

IgA Endomysial Antibodies (EMA)

IgA Tissue Transglutaminase (tTG)

Deamidated Gliadin Peptides (DGP)

Selective IgA Deficiency

Laboratory Differences

False Negatives/False Positives

Endoscopy and Biopsy (the Gold Standard for Diagnosis)

How Specific Is a Biopsy?

New European Standards for Children

Skin Biopsy

Gluten Challenge

Finger Prick Tests

Fecal Test

Saliva Testing

Breath Tests

Genetic Testing

Glutenostics-Gluten Detective Rapid Urine/Stool Test

The Future of Testing

5 Differential Diagnosis: Why Is Celiac Disease Underdiagnosed? 57

What Is the Differential Diagnosis of Celiac Disease?

Drugs That Mimic Celiac Disease

You Think You Are Sick, the Doctor Does Not

Finding a Doctor

Finding the Right Umbrella

6 Why Do People Get Celiac Disease? 67

A Brief History

The Crucial Pieces of the Puzzle

A Genetic Primer-Fitting the Groove

The Swedish Epidemic

The Hygiene Hypothesis

Epigenetics

What We Know

We Are Not There Yet

Part II Related Conditions and Complications 83

7 Neurological Manifestations 87

The Nervous System 101

Peripheral Neuropathy

Nerve Conduction Studies (EMG)

Ataxia

Epilepsy

Cerebral Calcifications: A Recognition Factor for Celiac Disease

Migraines

Other Neurological Conditions

Paralysis

What Causes Neuropathies in-Celiac Disease?

The Effect of the Gluten-Free Diet

8 Malignancy 98

The Relationship of Malignancies and Celiac Disease: What Is the Risk?

What Causes the Cancers?

Management Issues

The Effect of the Gluten-Free Diet

Should I Be Screened for Cancers?

9 Osteoporosis 105

Bones 101

Remodeling the Skeleton

The Reservoir Runs Dry

Are You at Risk?

What Causes Bone Loss in Celiac Disease?

Management Issues

The Effect of the Gluten-Free Diet

Diet and Supplements

Bone Resorption Agents

Parathyroid Hormone (PTH)

Exercise

10 Depression 117

What Is Depression?

What Causes Depression in Celiac Disease?

Nutrient Malabsorption-Folic Acid

The Effect of the Gluten-Free Diet

The Bottom Line

11 Dermatitis Herpetiformis and Other Skin Diseases 125

What Is Dermatitis Herpetiformis?

How Do I Know If I Have It-Tests for Dermatitis Herpetiformis

Where Does It Come From-Pathogenesis

Dermatitis Herpetiformis and Other Diseases

Bruising

Management Issues

Systemic Drugs

Topical Creams

What Triggers Dermatitis Herpetiformis?

The Effect of the Gluten-Free Diet

Hiding in Plain Sight

Other Skin Conditions

12 Diabetes 136

What Is Diabetes?

What Causes Type 1 Diabetes (IDDM)?

Diabetes and Celiac Disease

Management Issues

Lifestyle and Compliance Issues

Will I Get Better on a Gluten-Free Diet?

To Test or Not to Test

13 Infertility 146

What Causes Infertility?

The Relationship to Celiac Disease: Effect on Females

The Relationship to Celiac Disease: Effect on Males

What Causes Infertility in Celiac Disease?

The Effect of the Gluten-Free Diet

Next Steps

14 Autoimmune and Other Related Conditions 152

What Causes Autoimmune Disease?

Which Comes First?

Thyroid Disease

Sjögren's Syndrome

Addison's Disease

Autoimmune Liver Disease

Cardiomyopathy

Alopecia Areata

Lupus

Rheumatoid Arthritis

Fibromyalgia

Aphthous Stomatitis

Multiple Sclerosis (MS)

Autism Spectrum Disorder (ASD)

Attention-Deficit/Hyperactivity Disorder (ADHD)

Schizophrenia

Dental Enamel Defects

Raynaud's Syndrome

Genetic Disorders

A Final Word

Part III Understanding and Treating Celiac Disease: Medical Management 171

15 What You Need to Know-and Do-After Diagnosis 173

Treating the Patient, Not the Refrigerator

Dietary Counseling About the Gluten-Free Diet

Assessment of Nutritional Deficiencies

Medication Assessment

Bone Density Determination

Pneumococcal Vaccination

Screening of Family Members

Monitoring of Blood Antibody Levels

Repeat of Biopsy

Screening for Malignancies

General Health Measures

16 Why Symptoms Persist-I'm on the Diet and Not Betting Better 181

Lactose Intolerance

Pancreatic Insufficiency

Bacterial Overgrowth

Microscopic Colitis

Refractory Celiac Disease

Skin Manifestations

Forms of Gluten Ingestion

FODMAPs

How Soon Will I Get Better?

17 Follow-Up Testing 189

Follow-Up Blood Tests

Follow-Up Biopsy

Family Testing

High-Risk Group Testing

Genetic Testing

Video Capsule Endoscopy

Part IV The Diet: Do You Eat to Live or Live to Eat? 197

18 What Living Gluten-Free Really Means: The Basics 201

How Much Is Too Much?

Grain Science Cross Contamination

Basic Rules for Avoiding Cross Contamination Are You Getting Good Information?

19 Reading Labels 211

The 2014 Labeling Law

Labels 101

Ingredients and Additives Worth Understanding

Gluten-Free Labels

Testing for Gluten in a Product

Labels-The Next Steps

Questions That Remain

20 Cooking Without Gluten 219

Cooking Styles Cooking Gluten-Free

21 Eating in the Real World 225

Restaurants

Using Personal Technology to Help Detect Gluten

"Back-Home" Techniques

A Brief Sauce Primer

Other People's Homes

Hospital Stays

Travel

22 Family Occasions 238

Holidays-Dealing with the Urge to Splurge

Banquets and Wedding Bell Blues

23 The Medicine Cabinet and Cosmetics 241

Prescription Drugs

Vitamins, Minerals, and Other Supplements

Enzyme Supplements

Wheatgrass

Toothpaste

Cosmetics

24 Is Your Gluten-Free Diet Healthy? 246

Spare the Fat and Spoil the Cake?

Cholesterol/Triglycerides

Children at Risk

A Spoonful of Flax

Adults at Risk

Part V Living with Celiac Disease 251

25 Dealing with Children and Young Adults Who Have Celiac Disease 255

Factors That Affect Successful Adaptation

Parental Attitudes

The First Five (Birth to Five Years Old)

Six Ups (Six to Eleven Years Old)

Navigating School

Twelve Ups (Twelve to Eighteen Years Old, Adolescents) Adolescents with Celiac Disease and Type 1 Diabetes (IDDM)

Young Adults (College and Up)

Road Rules

26 Adults: Coping with Change 267

Reactions to the Diagnosis

Dealing with "Forbidden Fruit"

Passing the Pizza Test

Helpful Hints

27 Research: Finding a Cure 276

Potential Therapies

Designer Drugs

"First, Do No Harm"

The Future-Prevention of Celiac Disease

28 Myths and Unexplored Areas 285

Myths Surrounding Celiac Disease

Unexplored Areas

Appendix A A Guide to Ingredients 295

Appendix B Explanation of Grains 299

Appendix C Books and Articles of Interest 301

Appendix D Resources 306

Glossary 313

Index 325

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