Calcium-Binding Proteins in the Human Developing Brain

by N. Ulfig

Overview

"This book is primarily written for neuroscientists who will always be interested in the role of calcium in the internal neuronal environment. The objectives are well met. The authors are credible authorities in the field and are the most appropriate to discuss calcium in neuronal development...Through multiple excellent quality pictures, this book shows evidence of the potential roles of calcium in the modulation of development as well as on the determination of programmed cell death. " Review from Doody's Notes

Product Details

ISBN-13:	9783540434634
Publisher:	Springer Berlin Heidelberg
Publication date:	08/26/2002
Series:	Advances in Anatomy, Embryology and Cell Biology , #165
Edition description:	Softcover reprint of the original 1st ed. 2002
Pages:	96
Product dimensions:	6.10(w) x 9.25(h) x 0.10(d)

Table of Contents

1 Introduction.- 1.1 Calcium-Binding Proteins.- 1.2 CaBPs in the Mature and Developing Central Nervous System.- 1.3 Overview: Features of the Developing Brain.- 1.4 Scope of This Review.- 1.5 Materials and Methods.- 2 Cerebral Cortex: Subplate.- 2.1 Description.- 2.2 Expression of CaBPs in the Subplate.- 2.3 Functional Roles of the Subplate.- 2.4 Resolution of the Subplate.- 2.5 Effect of Fetal Hydrocephalus on the Distribution Pattern of CaBPs in the Subplate.- 2.6 Significance of the Subplate in Premature Infants.- 3 Cerebral Cortex: Cortical Plate.- 3.1 Description.- 3.2 CaBPs in the Cortical Plate.- 3.3 Effect of Fetal Hydrocephalus on the Distribution Pattern of CaBPs in the Cortical Plate.- 4 Cerebral Cortex: Molecular Layer (Layer I).- 4.1 Description.- 4.2 CaBPs in the Molecular Layer.- 4.3 Alterations in the Organization of Layer I in Trisomy 22.- 5 Ganglionic Eminence.- 5.1 Description.- 5.2 Developmental History.- 5.3 Neuronal Populations Originating from the Ganglionic Eminence.- 5.4 Calretinin and Calbindin Immunoreactive Cells in the Ganglionic Eminence and in the Intermediate Zone.- 5.5 The Ganglionic Eminence as an Intermediate Target.- 5.6 Significance of the Ganglionic Eminence in Developmental Neuropathology.- 6 Striatum.- 6.1 Description.- 6.2 Calbindin Expression in the Developing Striatum.- 6.3 Correlation of Calbindin Immunostaining and Expression of Synapse-Related Proteins in the Striatal Compartment of the Human Developing Brain.- 6.4 Significance of the Immunohishemical Findings in the Striatum for Developmental Neuropathology.- 7 Amygdala.- 7.1 Description.- 7.2 Transient Architectonic Features of the Amygdala.- 7.3 Nerve Cell Types in the Fetal Amygdala as Seen in Calbindin and Calretinin Immunopreparations.- 7.4 Diffuse Calbindin and Calretinin Immunostaining in the Human Fetal Amygdala.- 8 Basal Nucleus of Meynert.- 8.1 Description.- 8.2 Calbindin Immunoreactive Neurons in the Basal Nucleus of Meynert.- 8.3 Effect of Fetal Hydrocephalus on Neuronal Morphology in the Basal Nucleus of Meynert.- 9 Hypothalamic Tuberomamillary Nucleus.- 9.1 Description.- 9.2 Parvalbumin and Calretinin in the Tuberomamillary Nucleus.- 10 Thalamic Reticular Complex.- 10.1 Description.- 10.2 Main Portion.- 10.3 Perireticular Nucleus.- 10.4 Medial Subnucleus.- 10.5 Pregeniculate Nucleus.- 10.6 Neuronal Types of the Thalamic Reticular Complex as Seen in Parvalbumin and Calretinin Immunopreparations.- 11 Red Nucleus.- 11.1 Description.- 11.2 Distribution Pattern of CaBPs in the Developing and Adult Red Nucleus.- 11.3 Relationship Between the Magnocellular and Parvocellular Parts.- 11.4 Neurochemical Characteristics of Rubric Nerve Cells.- 11.5 The Magnocellular Part of the Red Nucleus in the Adult Human Brain.- 11.6 The Magnocellular Part of the Red Nucleus in the Developing Human Brain.- 11.7 Significance of the Prominent Magnocellular Part for Neuropediatrics.- 12 Summary.- References.

Editorial Reviews

Reviewer: Celso Agner, MD, MS, MSc (Michigan Neurology Partners)
Description: This book on calcium receptors in developing neurons seems to be a summary of multiple research projects developed over the years regarding the roles of calcium in the internal metabolism and in the metabolic cascades of cells.
Purpose: The objectives of this book are well-worth, in particular relating the potential roles of calcium as a modulator of internal metabolism of neurons but also on the determination of cell death, in some circumkstances. The interesting point of this book is, however, to demonstrate the effect of calcium in the modulation of neuronal development.
Audience: This book is primarily written for neuroscientists who will always be interested in the role of calcium in the internal neuronal environment. The objectives are well met. The authors are credible authorities in the field and are the most appropriate to discuss calcium in neuronal development.
Features: The 11 chapters in this short book are divided by anatomical regions and the possible representation of calcium receptors in neurons. Through multiple excellent quality pictures, this book shows evidence of the potential roles of calcium in the modulation of development as well as on the determination of programmed cell death. The price is, however, excessive.
Assessment: This is a good summary of the current understanding of the role of calcium in neuronal development. The book is expensive, but interested scientists may feel a need to include it in their libraries.

Doody's Review Service

3 Stars from Doody