Buprenorphine: Combatting Drug Abuse with a Unique Opioid / Edition 1

by Alan Cowan, John W. Lewis

Overview

Buprenorphine: Combatting Drug Abuse with a Unique Opioid

Editors: Alan Cowan and John W. Lewis

Scientists involved in the study of opioid pharmacology and drug abuse have long included among their goals the development of effective analgesics with reduced potential for abuse and dependence, and the development of effective pharmacological agents for the treatment of opioid abuse and dependence. Buprenorphine appears to have made an important scientific and clinical contribution on both of these fronts.

In this timely volume, international experts describe the unusual chemical and biological characteristics which make this agent unique, from the opiate receptor, through animal pharmacology, to clinical uses, culminating in a discussion of the use of buprenorphine as a medication in the treatment of opioid abuse.

Buprenorphine holds great promise as a significant addition to the therapeutic menu available to drug abuse therapists. Buprenorphine: Combatting Drug Abuse with a Unique Opioid will be indispensable to scientists and clinicians in pharmacology, neurobiology, psychiatry, neurology, and psychology, as well as to the wide spectrum of professionals involved in countering substance abuse.

Product Details

ISBN-13:	9780471561989
Publisher:	Wiley
Publication date:	03/10/1995
Pages:	344
Product dimensions:	6.30(w) x 9.50(h) x 1.10(d)

About the Author

Alan Cowan and John W. Lewis are the authors of Buprenorphine: Combatting Drug Abuse with a Unique Opioid, published by Wiley.

Table of Contents

Partial table of contents:

CHEMISTRY.

Buprenorphine-Medicinal Chemistry (J. Lewis).

PRECLINICAL PHARMACOLOGY.

Update on the General Pharmacology of Buprenorphine (A. Cowan).

ASSAY, METABOLISM, AND PHARMACOKINETICS.

Analysis (R. Moore).

CLINICAL PHARMACOLOGY AND EVALUATION.

Buprenorphine in Psychiatric Disorders (D. Nutt, et al.).

STUDIES RELATING TO TREATMENT OF SUBSTANCE ABUSE.

Detoxification and Induction Onto Naltrexone (M. Rosen & T. Kosten).

PERSPECTIVE.

Buprenorphine: What Interests the National Institute on Drug Abuse?

(D. Segal & C. Schuster).

Index.

Editorial Reviews

Reviewer: Michael Easton, MD (Rush University Medical Center)
Description: This is a highly specific and original book devoted to reviewing the majority of literature regarding a novel narcotic, buprenorphine.
Purpose: The purpose is to provide a thorough and comprehensive reference regarding buprenorphine. It gives detailed information regarding its pharmacology and preclinical data, specifically in regard to its addictive properties and its effects on the use of other narcotics and addicting drugs in animal models. This, in turn, helps one have a greater understanding of the elucidated human clinical studies in narcotic addicts. This book reviews a wide variety of uses of this agent in opiate addicts. It clearly evaluates its effectiveness in the acute detoxification of narcotic addicts along with the long term maintenance of these individuals. In addition, it highlights buprenorphine's potential usefulness in the treatment of other addictive disorders.
Audience: This is a highly specialized and valuable text geared toward individuals specialized in the pharmacotherapy of addictive disorders or opiate analgesics.
Features: This text contains numerous and useful charts, tables, and graphs. The references are numerous, up-to-date, and relevant.
Assessment: This is a highly specialized book devoted to the understanding of buprenorphine and its potentially unique role in the treatment of opiate and possibly other addictive disorders. It is geared to a highly specialized audience, but it is a book with which all specialists in the pharmacotherapy of addictive disorders should be familiar.

Doody's Review Service

3 Stars from Doody

This is a highly specific and original book devoted to reviewing the majority of literature regarding a novel narcotic, buprenorphine. The purpose is to provide a thorough and comprehensive reference regarding buprenorphine. It gives detailed information regarding its pharmacology and preclinical data, specifically in regard to its addictive properties and its effects on the use of other narcotics and addicting drugs in animal models. This, in turn, helps one have a greater understanding of the elucidated human clinical studies in narcotic addicts. This book reviews a wide variety of uses of this agent in opiate addicts. It clearly evaluates its effectiveness in the acute detoxification of narcotic addicts along with the long term maintenance of these individuals. In addition, it highlights buprenorphine's potential usefulness in the treatment of other addictive disorders. This is a highly specialized and valuable text geared toward individuals specialized in the pharmacotherapy of addictive disorders or opiate analgesics. This text contains numerous and useful charts, tables, and graphs. The references are numerous, up-to-date, and relevant. This is a highly specialized book devoted to the understanding of buprenorphine and its potentially unique role in the treatment of opiate and possibly other addictive disorders. It is geared to a highly specialized audience, but it is a book with which all specialists in the pharmacotherapy of addictive disorders should be familiar.

Michael Easton

Buprenorphine holds great promise as a significant addition to the therapeutic menu available to drug abuse therapists. In this volume, international experts describe the unusual chemical and biological characteristics which make this agent unique, from the opiate receptor, through animal pharmacology, to clinical uses, culminating in a discussion of the use of buprenorphine as a medication in the treatment of opioid abuse. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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