Biomaterials: The Intersection of Biology and Materials Science / Edition 1 available in Hardcover
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Biomaterials: The Intersection of Biology and Materials Science / Edition 1
![Biomaterials: The Intersection of Biology and Materials Science / Edition 1](http://img.images-bn.com/static/redesign/srcs/images/grey-box.png?v11.12.6)
Biomaterials: The Intersection of Biology and Materials Science / Edition 1
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Overview
Co-authors, Johnna Temenoff and Antonios Mikos, are the 2010 Meriam/Wiley Distinguished Author Award Recipients for Biomaterials: The Intersection of Biology and Materials Science.
Product Details
ISBN-13: | 2900130097100 |
---|---|
Publication date: | 01/02/2008 |
Pages: | 512 |
Product dimensions: | 6.50(w) x 1.50(h) x 9.50(d) |
About the Author
Table of Contents
Chapter 1: Materials for Biomedical Applications 1-11.1. Introduction to biomaterials 1-2
1.2. Biological response to biomaterials 1-8
1.3. Biomaterial product testing and FDA approval 1-10
1.4. Types of biomaterials 1-11
1.5. Processing of biomaterials 1-15
1.6. Important properties of biomaterials 1-16
1.7. Principles of chemistry 1-21
1.8. Summary 1-35
1.9. Problems 1-37
1.10. Tables 1-39
1.11. Figures 1-44
1.12. References 1-70
1.13. Additional reading 1-72
Chapter 2: Chemical Structure of Biomaterials 2-1
2.1. Introduction: Bonding and the structure of biomaterials 2-2
2.2. Structure of Metals 2-2
2.3. Structure of Ceramics 2-18
2.4. Structure of polymers 2-24
2.5. Techniques: Introduction to material characterization 2-41
2.6. Summary 2-62
2.7. Problems 2-64
2.8. Tables 2-69
2.9. Figures 2-79
2.10. References 2-148
2.11. Additional reading 2-149
Chapter 3: Physical Properties of Biomaterials 3-1
3.1. Introduction: From atomic groupings to bulk materials 3-2
3.2. Crystallinity and linear defects 3-2
3.3. Crystallinity and planar defects 3-8
3.4. Crystallinity and volume defects 3-12
3.5. Crystallinity and polymeric materials 3-13
3.6. Thermal transitions of crystalline and non-crystalline materials 3-18
3.7. Techniques: Introduction to Thermal Analysis 3-26
3.8. Summary 3-30
3.9. Problems 3-32
3.10. Tables 3-35
3.11. Figures 3-38
3.12. References 3-63
3.13. Additional reading 3-64
Chapter 4: Mechanical Properties of Biomaterials 4-1
4.1. Introduction: Modes of mechanical testing 4-3
4.2. Mechanical testing methods, results and calculations 4-3
4.3. Fracture and failure 4-40
4.4. Fatigue and fatigue testing 4-43
4.5. Methods to improve mechanical properties 4-46
4.6. Techniques: Introduction to Mechanical Analysis 4-49
4.7. Summary 4-51
4.8. Problems 4-54
4.9. Figures 4-58
4.10. References 4-101
4.11. Additional reading 4-101
Chapter 5: Biomaterial Degradation 5-1
5.1. Introduction: Degradation in the biological environment 5-2
5.2. Corrosion/degradation of metals and ceramics 5-3
5.3. Degradation of polymers 5-18
5.4. Biodegradable materials 5-22
5.5. Techniques: Assays for extent of degradation 5-29
5.6. Summary 5-30
5.7. Problems 5-32
5.8. Tables 5-37
5.9. Figures 5-40
5.10. References 5-54
5.11. Additional reading 5-55
Chapter 6: Biomaterial Processing 6-1
6.1. Introduction: Importance of biomaterials processing 6-2
6.2. Processing to improve bulk properties 6-2
6.3. Processing to form desired shapes 6-12
6.4. Processing to improve biocompatibility 6-26
6.5. Summary 6-30
6.6. Problems 6-32
6.7. Tables 6-34
6.8. Figures 6-35
6.9. References 6-54
6.10. Additional reading 6-55
Chapter 7: Surface Properties of Biomaterials 7-1
7.1. Introduction: Concepts in surface chemistry and biology 7-2
7.2. Physicochemical surface modification techniques 7-6
7.3. Biological surface modification techniques 7-20
7.4. Surface properties and degradation 7-25
7.5. Patterning techniques for surfaces 7-25
7.6. Techniques: Introduction to surface characterization 7-27
7.7. Summary 7-46
7.8. Problems 7-48
7.9. Tables 7-53
7.10. Figures 7-58
7.11. References 7-107
7.12. Additional reading 7-109
Chapter 8: Protein Interactions with Biomaterials 8-1
8.1. Introduction: Thermodynamics of protein adsorption 8-2
8.2. Protein structure 8-7
8.3. Protein transport and adsorption kinetics 8-15
8.4. Reversibility of protein adsorption 8-18
8.5. Techniques: Assays for protein type and amount 8-22
8.6. Summary 8-33
8.7. Problems 8-35
8.8. Tables 8-39
8.9. Figures 8-42
8.10. References 8-74
8.11. Additional reading 8-75
Chapter 9: Cell Interactions with Biomaterials 9-1
9.1. Introduction: Cell-surface interactions and cellular functions 9-2
9.2. Cellular structure 9-3
9.3. Extracellular environment 9-14
9.4. Cell-environment interactions affect cellular functions 9-23
9.5. Models of adhesion, spreading and migration 9-34
9.6. Techniques: Assays to determine effects of cell-material interactions 9-43
9.7. Summary 9-53
9.8. Problems 9-57
9.9. Tables 9-61
9.10. Figures 9-62
9.11. References 9-113
9.12. Additional reading 9-115
Chapter 10: Biomaterial Implantation and Acute Inflammation 10-1
10.1. Introduction: Overview of innate and acquired immunity 10-2
10.2. Clinical signs of inflammation and their causes 10-5
10.4. Role of other granulocytes 10-11
10.5. Termination of acute inflammation 10-16
10.6. Techniques: In vitro assays for inflammatory response 10-17
10.7. Summary 10-20
10.8. Problems 10-22
10.9. Tables 10-24
10.10. Figures 10-27
10.11. References 10-34
10.12. Additional reading 10-34
Chapter 11: Wound Healing and the Presence of Biomaterials 11-1
11.1. Introduction: Formation of granulation tissue 11-2
11.2. Foreign body reaction 11-3
11.3. Fibrous encapsulation 11-4
11.4. Chronic inflammation 11-7
11.5. Four types of resolution 11-8
11.6. Repair vs. regeneration: wound healing in skin 11-9
11.7. Techniques: In vivo assays for inflammatory response 11-12
11.8. Summary 11-20
11.9. Problems 11-22
11.10. Tables 11-25
11.11. Figures 11-28
11.12. References 11-36
11.13. Additional reading 11-37
Chapter 12: Immune Response to Biomaterials 12-1
12.1. Introduction: Overview of acquired immunity 12-2
12.2. Antigen presentation and lymphocyte maturation 12-4
12.3. B cells and antibodies 12-8
12.4. T cells 12-12
12.5. The complement system 12-14
12.6. Undesired immune responses to biomaterials 12-19
12.7. Techniques: Assays for immune response 12-25
12.8. Summary 12-28
12.9. Problems 12-32
12.10. Tables 12-34
12.11. Figures 12-35
12.12. References 12-51
12.13. Additional reading 12-51
Chapter 13: Biomaterials and Thrombosis 13-1
13.1. Introduction: Overview of hemostasis 13-2
13.2. Role of platelets 13-2
13.3. Coagulation cascade 13-5
13.4. Means of limiting clot formation 13-9
13.5. Role of endothelium 13-11
13.6. Tests for hemocompatibility 13-13
13.7. Summary 13-18
13.8. Problems 13-20
13.9. Tables 13-25
13.10. Figures 13-27
13.11. References 13-32
13.12. Additional reading 13-33
Chapter 14: Infection, Tumorigenesis and Calcification of Biomaterials 14-1
14.1. Introduction: Overview of other potential problems with biomaterials implantation 14-2
14.2. Infection 14-2
14.3. Techniques for infection experiments 14-10
14.4. Tumorigenesis 14-16
14.5. Techniques for tumorigenesis experiments 14-21
14.6. Pathologic calcification 14-23
14.7. Techniques for pathologic calcification experiments 14-26
14.8. Summary 14-30
14.9. Problems 14-33
14.10. Figures 14-36
14.11. References 14-45
14.12. Additional reading 14-46
List of Abbreviations Appendix I-1
List of Symbols Appendix I-6
Index Index