Benzodiazepines
Developed decades ago to treat a legitimate medical need, benzodiazepines promisingly displaced less-effective and less-safe drugs, though prescribing has since exceeded their intended use and outpaced the available data. The current situation is characterized by excessive prescribing and extended utilization beyond good therapeutic practice. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. The Benzodiazepines Crisis sounds the alarm against the overuse of benzodiazepines, presenting an updated, evidence-based overview of this class of drugs and their negative consequences. Bringing together years of research, clinical expertise, and scientific evidence, this book aims to address a perceived lag between evidence and action in order to call for rational and dramatically reduced usage of benzodiazepines.
1137898060
Benzodiazepines
Developed decades ago to treat a legitimate medical need, benzodiazepines promisingly displaced less-effective and less-safe drugs, though prescribing has since exceeded their intended use and outpaced the available data. The current situation is characterized by excessive prescribing and extended utilization beyond good therapeutic practice. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. The Benzodiazepines Crisis sounds the alarm against the overuse of benzodiazepines, presenting an updated, evidence-based overview of this class of drugs and their negative consequences. Bringing together years of research, clinical expertise, and scientific evidence, this book aims to address a perceived lag between evidence and action in order to call for rational and dramatically reduced usage of benzodiazepines.
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Benzodiazepines

Benzodiazepines

by John Peppin
Benzodiazepines

Benzodiazepines

by John Peppin

eBook

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Overview

Developed decades ago to treat a legitimate medical need, benzodiazepines promisingly displaced less-effective and less-safe drugs, though prescribing has since exceeded their intended use and outpaced the available data. The current situation is characterized by excessive prescribing and extended utilization beyond good therapeutic practice. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. The Benzodiazepines Crisis sounds the alarm against the overuse of benzodiazepines, presenting an updated, evidence-based overview of this class of drugs and their negative consequences. Bringing together years of research, clinical expertise, and scientific evidence, this book aims to address a perceived lag between evidence and action in order to call for rational and dramatically reduced usage of benzodiazepines.

Product Details

ISBN-13: 9780197517291
Publisher: Oxford University Press
Publication date: 10/01/2020
Sold by: Barnes & Noble
Format: eBook
Pages: 256
File size: 7 MB

About the Author

John F. Peppin, DO, FACP Hamden, CT Robert B. Raffa, PhD Tucson, AZ Joseph V. Pergolizzi Jr, MD Naples FL Steven Wright, MD Denver, CO

Table of Contents

Forewords Reid Finlayson, Lynn Webster, Bernie Silvernail, and Carrie Silvernail Preface John F. Peppin, Joseph V. Pergolizzi, Jr., Robert B. Raffa, and Steven Wright 1. Introduction: Anxiety, Insomnia, and Benzodiazepines Michael M. Miller John Peppin 2. The Evolution of Benzodiazepines and the 'Z' Drugs Jamie L. Hansen and Timothy J. Atkinson 3. Uses, Efficacy, and Adverse Effects of Benzodiazepines Brian Merrill and Jeffrey Guina 4. Problems with Benzodiazepine Use in the Elderly Jan Kitzen 5. Benzodiazepine Receptors in the Brain Michael H. Ossipov 6. Benzodiazepine Receptors in the Periphery Robert B. Raffa 7. Benzodiazepine Withdrawal: Neurobiologic Aspects George F. Koob 8. Benzodiazepine Withdrawal: Clinical Aspects Steven Wright 9. Benzodiazepines and Pain John F. Peppin and Steven Wright 10. Benzodiazepines Abuse John J. Coleman 11. History of the Regulatory Control of Benzodiazepines John J. Coleman 12. Guidelines and Guidances Jo Ann LeQuang 13. The Benzodiazepine Legacy Patient Jeffrey Guina and Brian Merrill 14. Perspective John Peppin
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