Atrial Fibrillation: New Therapeutic Concepts

by J.G. Papp, M. Straub, D. Ziegler

Overview

Work from a November 2001 conference sponsored by Solvay Pharmaceuticals looks at recent research in the treatment of atrial fibrillation and reviews different aspects of the disorder's pathophysiology, epidemiology, and current therapy. The book evaluates progress achieved by molecular biology in recent years in identifying ion channel proteins and genetic defects related to atrial fibrillation, and highlights new avenues of current research on more effective and safer treatments. There is no subject index. Annotation ©2004 Book News, Inc., Portland, OR

Product Details

ISBN-13:	9781586033873
Publisher:	IOS Press, Incorporated
Publication date:	01/01/2003
Series:	Solvay Pharmaceuticals Conferences Series
Pages:	168
Product dimensions:	9.66(w) x 6.48(h) x 0.65(d)

Table of Contents

	Preface	v
	List of Contributors	vi
	Conference Preface	3
	Keynote Lecture - Atrial Fibrillation: The Last Frontier in Antiarrhythmic Therapy?	5
	Physiology of Cardiac K[superscript +] Channels: New Aspects of Channel Regulation	13
	Pharmacology of Potassium Channel Blockers	27
	Mechanisms of Antiarrhythmic Actions in the Maintenance of Sinus Rhythm in Patients with Atrial Fibrillation: Clinical and Experimental Correlations	41
	The Epidemiology and Classification of Atrial Fibrillation	57
	Antiarrhythmic Drugs for the Acute Conversion of Atrial Fibrillation and Flutter to Sinus Rhythm: What We Have and What We Need	71
	Critical Evaluation of Drugs for Maintenance of Normal Sinus Rhythm or Control of Ventricular Rate in Atrial Fibrillation	81
	Non-pharmacological Therapies for Atrial Fibrillation	93
	Critical Appraisal of Available Models for Detecting Proarrhythmic Side-effects of Compounds	103
	Molecular Biology of Potassium Channels and the Long QT Syndrome	115
	New Mechanistic Targets for the Treatment of Atrial Fibrillation	133
	Author Index	157