Animal Electricity: How We Learned That the Body and Brain Are Electric Machines

Animal Electricity: How We Learned That the Body and Brain Are Electric Machines

by Robert B. Campenot
Animal Electricity: How We Learned That the Body and Brain Are Electric Machines

Animal Electricity: How We Learned That the Body and Brain Are Electric Machines

by Robert B. Campenot

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Overview

Like all cellular organisms, humans run on electricity. Slight imbalances of electric charge across cell membranes result in sensation, movement, awareness, and thinking—nearly everything we associate with being alive. Robert Campenot offers a comprehensive overview of animal electricity, examining its physiological mechanisms as well as the experimental discoveries that form the basis for our modern understanding of nervous systems across the animal kingdom.

Cells work much like batteries. Concentration gradients of sodium and potassium cause these ions to flow in and out of cells by way of protein channels, creating tiny voltages across the cell membrane. The cellular mechanisms that switch these ion currents on and off drive all the functions associated with animal nervous systems, from nerve impulses and heartbeats to the 600-volt shocks produced by electric eels.

Campenot’s examination of the nervous system is presented in the context of ideas as they evolved in the past, as well as today’s research and its future implications. The discussion ranges from the pre-Renaissance notion of animal spirits and Galvani’s eighteenth-century discovery of animal electricity, to modern insights into how electrical activity produces learning and how electrical signals in the cortex can be used to connect the brains of paralyzed individuals to limbs or prosthetic devices. Campenot provides the necessary scientific background to make the book highly accessible for general readers while conveying much about the process of scientific discovery.


Product Details

ISBN-13: 9780674495586
Publisher: Harvard University Press
Publication date: 02/15/2016
Sold by: Barnes & Noble
Format: eBook
Pages: 352
File size: 3 MB

About the Author

Robert B. Campenot is Professor Emeritus in the Department of Cell Biology at the University of Alberta.

Table of Contents

Cover Title Copyright Dedication Contents Preface Introduction Chapter 1: Animal Electricity The Heat Theory of the Elevator Button Voltage, Charge, Current, Resistance, and Capacitance The Capacitance Theory of the Elevator Button The Leyden Jar Animal Electricity Chapter 2: A World of Cells, Molecules, and Atoms The World of the Unaided Eye Entering the Unseen World The Cell Membrane Chapter 3: The Animal Battery The Sodium-Potassium Exchange Pump The Potassium Battery The Electric Model of the Cell Membrane Voltage-Activated Gating Chapter 4: Hodgkin and Huxley before the War Primitive Equipment Lucas’s and Adrian’s Experiments Before the Squid The Squid Giant Axon Chapter 5: The Mystery of Nerve Conduction Explained The Sodium Theory The Voltage Clamp The Traveling Action Potential The Strange Case of the Jumping Action Potential Chapter 6: Heart to Heart The Axon Chemical Synaptic Transmission Neurotransmitters Galore Chapter 7: Nerve to Muscle Fatt, Katz, and Curare The Excitatory Postsynaptic Potential Synaptic Vesicles The Response to Acetylcholine Chemical Transmission is Fast Enough Mechanism of Muscle Contraction Synapses in the Brain and Spinal Cord Chapter 8: Use It or Lose It Development of the Nervous System Nerve Growth Factor Electrical Activity and the Development of the Visual System “Slicing” Into the Brains of Live Humans The “Meaning” of Cortical Circuitry Memory Circuits Memories in the Brain Chapter 9: Broadcasting in the Volume Conductor Torpedo Rays and Electric Eels Ocean of Electricity The Electrocardiogram The Pumping Heart The Beat Goes on Broadcasts from the Brain The Fringe Speculation What Scientists Know Chapter 10: The Bionic Century The Problem of Nerve Regeneration Mind-Reading Prosthetics Bionic Ears Bionic Eyes Conclusion Epilogue Notes References Acknowledgments Index
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