Animal Clinical Chemistry: A Practical Handbook for Toxicologists and Biomedical Researchers, Second Edition / Edition 1

by G.O. Evans

Overview

By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science.

Product Details

ISBN-13:	9780748403516
Publisher:	Taylor & Francis
Publication date:	04/29/1996
Pages:	224
Product dimensions:	7.00(w) x 10.00(h) x (d)

Table of Contents

Study design and regulatory requirements; pre-analytical and analytical variables; statistical approaches; enzymes; assessment of hepatotoxicity; assessment of nephrotoxicity; assessment of endocrine toxicity; assessment of gastrointestinal toxicity; assessment of cardiotoxicity and myotoxicity; assessment of neurotoxicity; electrolytes; lipids; proteins.

Editorial Reviews

… a welcome update to the 1996 first edition. It is great to see that the new edition retains the highly useful (and extensive) reference list at the end of each chapter. … Overall, this book represents a valuable addition to the toxicologist’s armory, both for those new in the field and those a bit longer in the tooth!
—Paul Baldrick, in The British Toxicology Society Newsletter, Winter 2009, Issue 35

Praise for the Previous Edition:

… a very well written and concise book, which ought to reach a much wider audience than toxicologists. It addresses normal and abnormal clinical chemistry of laboratory animals and is thus of relevance to the large segment of the biomedical research community making use of animal models in their research.
—Jann Hau, Chair of Comparative Medicine and Head of the Department of Experimental Medicine, University of Copenhagen and State Hospital

… produced to a high standard, consistent style, and of clear relevance to toxicology …. a timely, practical, and useful addition to the literature. It is highly recommended both for toxicology courses and functional laboratories and will no doubt be regarded as a standard text in the field.
—Phillip Harvey, AgrEvo UK Ltd, in The British Toxicology Society Newsletter, December 1996

From the Publisher