Alginates in Drug Delivery

by Amit Kumar Nayak PhD (Editor), Md Saquib Hasnain Ph.D (Editor)

Overview

Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field.

This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences.

• Provides a single source on the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields
• Includes high quality illustrations, along with practical examples and research case studies
• Contains contributions by global leaders and experts from academia, industry and regulatory agencies who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields

Product Details

ISBN-13:	9780128176412
Publisher:	Elsevier Science
Publication date:	07/23/2020
Sold by:	Barnes & Noble
Format:	eBook
Pages:	434
File size:	22 MB
Note:	This product may take a few minutes to download.

About the Author

Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.

Prof. (Dr.) Md Saquib Hasnain has over 10 years of research experience in the field of drug delivery and pharmaceutical formulation analyses, especially systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, nanomaterials and nanocomposites employing Quality by Design approaches and many more. Till date he has authored over 70 publications in various high impact peer-reviewed journals, more than 100 book chapters and 16 books to his credit. He is also serving as the reviewer of several prestigious journals. Overall, he has earned a highly impressive publishing and cited record in Google Scholar (h-index: 32). He has also participated and presented his research work at over ten conferences in India, and abroad. He was also a member of scientific societies i.e., Royal Society of Chemistry, Great Britain, International Association of Environmental and Analytical Chemistry, Switzerland and Swiss Chemical Society, Switzerland.

Table of Contents

1. Introduction to alginates as drug delivery excipient 2. Alginate hydrogels for drug delivery applications 3. Alginate nanoparticles in drug delivery 4. Ionotropically gelled alginate-based multiple-unit matrices in sustained drug release 5. Physically and chemically modified alginates in drug delivery 6. Grafted alginates in drug delivery 7. Alginate-based interpenetrating polymer networks for sustained drug release 8. Biocomposites of alginates in drug delivery 9. Alginate-inorganic composite matrices as drug releasing carriers 10. Buoyant particles of alginates in floating drug delivery 11. Alginate-based hydrogel membranes for drug releasing in wound healing 12. Alginate-based scaffolds for drug delivery in tissue engineering

What People are Saying About This

From the Publisher

Provides insight into the complete alginate chemistry, collection, chemical modifications, characterization and applications of alginate in the healthcare field

Editorial Reviews

Reviewer: Rahmat M. Talukder, PhD, RPh (The University of Texas at Tyler)
Description: This book offers a wide range of topics on the application of alginates in developing drug delivery systems. It is well referenced with sufficient illustrations.
Purpose: This reference aims to present a comprehensive review of various aspects of alginates, especially their applications in pharmaceutical preparations. Alginates, natural biopolymers, are mainly obtained from marine algae. These non-toxic, water-soluble, linear, biodegradable polymers have been used in food, biomedical, and pharmaceutical products. Thus, a single source of information on the chemistry and application of these polymers in the pharmaceutical preparation is useful to the formulation scientist.
Audience: The editors believe this reference should be useful to individuals involved in pharmaceutical and healthcare products. This book presents the basic chemistry and pharmaceutical use of alginates. Thus, it is expected to be useful to the scientist who intends to learn the application of alginates. Faculty members and scientists from different universities in Asia have contributed to this book.
Features: The wide-ranging topics are presented in 15 chapters. The first two chapters discuss the fundamental chemistry, source, and common pharmaceutical use of alginates. The subsequent chapters detail applications of alginates in the development of various pharmaceutical dosage forms, including fabrication of hydrogel, nanoparticles, composites, sustained drug delivery systems, etc. Additional chapters discuss the application of alginates in developing wound healing dressings and drug delivery systems for the treatment of dental conditions. A chapter on the fabrication of alginate-based scaffolds as drug delivery systems is applicable in tissue engineering. Though brief, the chapter presents different techniques employed in the preparation of scaffolds, which are expected to be useful to the readers. While the book includes sufficient illustrations, the quality of those illustrations could be much better, mostly had they been colored. Chapter 7 presents a table on the application of alginate biocomposites; the author could have included several more items related to alginate composites' medical use.
Assessment: Alginates are naturally occurring bio-polysaccharides, which afford their application in biomedical and pharmaceutical preparations. This book presents a comprehensive review of the use of alginates in the fabrication of various drug delivery systems. In 2019, the editors of this book published another book titled Alginates: Versatile Polymers in Biomedical Applications and Therapeutics (CRC Press). There are overlaps of some topics between the two books. This book, however, focuses primarily on the application of alginates in pharmaceutical preparations. Thus, it is expected to be well utilized by its target audience.

Doody's Review Service

"Alginates are naturally occurring biopolysaccharides, which afford their application in biomedical and pharmaceutical preparations. This book presents a comprehensive review of the use of alginates in the fabrication of various drug delivery systems. In 2019, the editors of this book published another book titled Alginates: Versatile Polymers in Biomedical Applications and Therapeutics (CRC Press). There are overlaps of some topics between the two books. This book, however, focuses primarily on the application of alginates in pharmaceutical preparations. Thus, it is expected to be well utilized by its target audience" —Doody

From the Publisher