Adverse Events: Race, Inequality, and the Testing of New Pharmaceuticals

Adverse Events: Race, Inequality, and the Testing of New Pharmaceuticals

by Jill A. Fisher

Narrated by Diana Blue

Unabridged — 13 hours, 0 minutes

Adverse Events: Race, Inequality, and the Testing of New Pharmaceuticals

Adverse Events: Race, Inequality, and the Testing of New Pharmaceuticals

by Jill A. Fisher

Narrated by Diana Blue

Unabridged — 13 hours, 0 minutes

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Overview

Imagine that you volunteer for the clinical trial of an experimental drug. The only direct benefit of participating is that you will receive up to $5,175. You must spend twenty nights literally locked in a research facility. You will be told what to eat, when to eat, and when to sleep. You will share a bedroom with several strangers. Who are you, and why would you choose to take part in this kind of study?



This book explores the hidden world of pharmaceutical testing on healthy volunteers. Drawing on two years of fieldwork in clinics across the country and 268 interviews with participants and staff, it illustrates how decisions to take part in such studies are often influenced by poverty and lack of employment opportunities. It shows that healthy participants are typically recruited from African American and Latino/a communities, and that they are often serial participants, who obtain a significant portion of their income from these trials.



This book reveals not only how social inequality fundamentally shapes these drug trials, but it also depicts the important validity concerns inherent in this mode of testing new pharmaceuticals. These highly controlled studies bear little resemblance to real-world conditions, and everyone involved is incentivized to game the system, ultimately making new drugs appear safer than they really are.

Editorial Reviews

For Better Science

"Especially during the COVID-19 pandemic, its message is very important."

New York Review of Books

"Jill Fisher has provided the most thorough examination [of Phase I trials] yet … the world that Fisher reveals in Adverse Events is unsettling."

Social Forces

"Jill Fisher invites the reader into a sustained and systematic analysis of how pharmaceutical companies operate their Phase I drug trials and the symbiotic relationship between drug development and what she calls a “profound economic insecurity” on the part of the participants ... It is an important book for understanding broader sociological concepts of inequality, stigma, and pharmaceutical development."

Stefan Timmermans

"A mesmerizing ethnographic study that shows the safety of the pharmaceuticals we swallow depends on an invisible army of volunteers putting their bodies at risk for a quick dollar."

The New Republic

"Adverse Events damns the industry with simple description, but Fisher’s analysis has a bigger concern. The industry is a symptom of the American problem of racist capitalism, and in the book, Fisher documents how a racist, wildly unequal economy leads people who are already in precarious positions to take part in first-in-human trials. Ten years ago, when she started her research, she could hardly have predicted its immediacy."

Carl Elliott

"One of the best books of medical sociology I have ever read. Fisher describes the world of paid research subjects with remarkable insight and compassion. . . . Nothing short of brilliant."

Medical Anthropology Quarterly

"Adverse Events reveals the many and varied ways in which social inequalities—particularly class and race—compel individuals to become healthy volunteers for Phase I trials, despite the risks involved ... This is a text that can—and should—reach audiences beyond academia."

New Genetics and Society

"Leaves a striking impression on the reader ... Likely to be of interest to a broad audience. It is suitable for lay people who have an interest in exploring a largely unseen side of the pharmaceutical industry, people working in pharmaceuticals who wish to scrutinize the ins-and-outs of their industry, as well as students and academics such as bioethicists, sociologists, and those studying race and ethnicity"

Donald W. Light

"May become a scholarly classic, change how the drugs we take are tested, and save billions in misleading trials that are not necessary."

CHOICE

"This book presents weighty implications relative to current US economic and employment arrangements ... a helpful reference in courses on bioethics, biomedical research methods, social justice, gender and race/ethnicity, intersectionality studies, and the sociology of science."

Jeremy Greene

"Offers an unflinching view of the inequities built in to the twenty-first-century clinical-trials industry. . . . Has as much to say about the micropolitics of stigma and adversity as it does about the macrostructures of health and capitalism today."

Product Details

BN ID: 2940176396355
Publisher: Tantor Audio
Publication date: 04/06/2021
Edition description: Unabridged
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