Advancing the art of medical diagnoses:3
Stress could be physical, metabolic and psychological, and it triggers cellular changes inside the body including transcription induction changes leading to various secretions as well as myriads of phenotype changes in diverse body tissues. MAPK/JANUS KINASE, pathway of cellular protein synthesis transcription induction via stress receptors is the basis for such changes. Bowel flora and fauna vary in different segments of bowel in the human body so also their interactive effects with stress are different. Current literature review of papers, journals, abstracts, textbooks both in pubmed and cochrane data base, of more than 300 documents did not reveal any information on pattern of stress interaction with different bowel segments hence, this study filled in a piece of relevant but missing information in the body of medicine.
The study was an observational, case cross comparison ,retrospective, mixed method research study.Clear pictures, diagram sketches, tables, motion pictures, and laboratory results data of relevant patients case notes were used and the case notes were either summarized or written in full to buttress the point were relevant.
The study found out the following:
1. Stressed single females aged 15-55years are prone to typhoid perforation, arising from salmonella typhi D, and paratyphi A, infections at a lower widal reaction titres of 1in 160, contrary to previous literature, 1in 320 titre; while stressed males 30-55 years are more prone to gastric perforations and at older age >70 years gastric cancers.
2. It enhanced the understanding of the GUT-BRAIN response to pain.while the spino-thalamic reflex releases natural opioids[beta endorphins] to relief pain, the spino adrenergic segment cause the circular and longitudinal smooth muscles of the bowel to contract and shut down peristalsis to limit spread of noxious/injurious substance to the unaffected parts of the gut,the spino-serotogenic response causes rapid fluid accumulation to further dilute the noxious substance in the bowel lumen and the stasis and fluid accumulation lead to vomiting either projectile or non-projectile. Adhesion formation from either omentum majus to posterior abdominal wall, across the bowel, or bowel looping on top of on another, in a new connective tissue web film, are ways on ensuring that the stasis prevents spillage of intestinal content from one segment to another 100%.
3. Although current literature showed salmonella typhi d as resident in mucosa of ileum it failed to show how it reached the peritoneum from there since on its own alone it could not pass beyond the vascular endothelium. Mast cell[TC] group secrete chymase which is capable of dissolving both vascular endothelium as well as epithelium of parietal and visceral peritoneum hence making way for the salmonella organism to reach the peritoneal cavity from the bowel lumen.
4. This study showed that mast cell population density varied in the bowel region viz: 1.small density on anti-mesenteric surface of jejenum or ileum. 2. medium density on distal 1/3 of small intestinal mesentery, 3.maximum density on proximal 1/3 of small intestinal mesentery. So rupture of epithelia as well as vascular endothelium, in all three different locations stated above, were all possible in the three different locations and they are almost always involved in pathology of ruptured intestine.
5. The study reported the following, four cases, which were, first time cases world wide:
1. 53 years old woman with 1st 34 cm of jejenum perforating, at 10, and 33cm from duodeno-jejenal junction, causing serial changes, of adherent omentum majus,adhesive obstruction at jejeno-ileal junction, adhesion of pylorus to liver at neck of gall bladder, plus 3 gall stones of progressively decreasing sizes amongst others.
2. In a 35 years old gravid female, the anterior wall of the uterus perforated and became adherent to gastric epiploicae of the sigmoid colon with dense new adipose tissue formation prior to conception and implantation. Fibromyotic and adenomyotic changes were limited to the 5cm diameter area of the perforation while the rest of the uterine smooth muscle were good.
3. In a 28 year old female, Acute Necrotizing Fascitis, consumed the right ovary and salpinx 100% with dry charcoal residues seen while the left ovary and salpinx were intact and functional.More will come in a subsequent publication,'Advancing the art of medical diagnosis part 5'. Male factor in female infertility and fibrogenesis.
4. Haemolysin virulent factor,from staph aureus has ,beta, alpha, miu, delta antigens, and when transcribed in a distant location like the left breast, from primary site of infection like the vulva vagina region, it causes, multilocular fibrocystic mass brownish color for its alpha or beta variety while the delta variety causes diagona
6.Finally, get your own copy of this book today to get a hold of the moving world of medical science.WE live in a rapidly changing world so don't be left out.
"1141804342"
The study was an observational, case cross comparison ,retrospective, mixed method research study.Clear pictures, diagram sketches, tables, motion pictures, and laboratory results data of relevant patients case notes were used and the case notes were either summarized or written in full to buttress the point were relevant.
The study found out the following:
1. Stressed single females aged 15-55years are prone to typhoid perforation, arising from salmonella typhi D, and paratyphi A, infections at a lower widal reaction titres of 1in 160, contrary to previous literature, 1in 320 titre; while stressed males 30-55 years are more prone to gastric perforations and at older age >70 years gastric cancers.
2. It enhanced the understanding of the GUT-BRAIN response to pain.while the spino-thalamic reflex releases natural opioids[beta endorphins] to relief pain, the spino adrenergic segment cause the circular and longitudinal smooth muscles of the bowel to contract and shut down peristalsis to limit spread of noxious/injurious substance to the unaffected parts of the gut,the spino-serotogenic response causes rapid fluid accumulation to further dilute the noxious substance in the bowel lumen and the stasis and fluid accumulation lead to vomiting either projectile or non-projectile. Adhesion formation from either omentum majus to posterior abdominal wall, across the bowel, or bowel looping on top of on another, in a new connective tissue web film, are ways on ensuring that the stasis prevents spillage of intestinal content from one segment to another 100%.
3. Although current literature showed salmonella typhi d as resident in mucosa of ileum it failed to show how it reached the peritoneum from there since on its own alone it could not pass beyond the vascular endothelium. Mast cell[TC] group secrete chymase which is capable of dissolving both vascular endothelium as well as epithelium of parietal and visceral peritoneum hence making way for the salmonella organism to reach the peritoneal cavity from the bowel lumen.
4. This study showed that mast cell population density varied in the bowel region viz: 1.small density on anti-mesenteric surface of jejenum or ileum. 2. medium density on distal 1/3 of small intestinal mesentery, 3.maximum density on proximal 1/3 of small intestinal mesentery. So rupture of epithelia as well as vascular endothelium, in all three different locations stated above, were all possible in the three different locations and they are almost always involved in pathology of ruptured intestine.
5. The study reported the following, four cases, which were, first time cases world wide:
1. 53 years old woman with 1st 34 cm of jejenum perforating, at 10, and 33cm from duodeno-jejenal junction, causing serial changes, of adherent omentum majus,adhesive obstruction at jejeno-ileal junction, adhesion of pylorus to liver at neck of gall bladder, plus 3 gall stones of progressively decreasing sizes amongst others.
2. In a 35 years old gravid female, the anterior wall of the uterus perforated and became adherent to gastric epiploicae of the sigmoid colon with dense new adipose tissue formation prior to conception and implantation. Fibromyotic and adenomyotic changes were limited to the 5cm diameter area of the perforation while the rest of the uterine smooth muscle were good.
3. In a 28 year old female, Acute Necrotizing Fascitis, consumed the right ovary and salpinx 100% with dry charcoal residues seen while the left ovary and salpinx were intact and functional.More will come in a subsequent publication,'Advancing the art of medical diagnosis part 5'. Male factor in female infertility and fibrogenesis.
4. Haemolysin virulent factor,from staph aureus has ,beta, alpha, miu, delta antigens, and when transcribed in a distant location like the left breast, from primary site of infection like the vulva vagina region, it causes, multilocular fibrocystic mass brownish color for its alpha or beta variety while the delta variety causes diagona
6.Finally, get your own copy of this book today to get a hold of the moving world of medical science.WE live in a rapidly changing world so don't be left out.
Advancing the art of medical diagnoses:3
Stress could be physical, metabolic and psychological, and it triggers cellular changes inside the body including transcription induction changes leading to various secretions as well as myriads of phenotype changes in diverse body tissues. MAPK/JANUS KINASE, pathway of cellular protein synthesis transcription induction via stress receptors is the basis for such changes. Bowel flora and fauna vary in different segments of bowel in the human body so also their interactive effects with stress are different. Current literature review of papers, journals, abstracts, textbooks both in pubmed and cochrane data base, of more than 300 documents did not reveal any information on pattern of stress interaction with different bowel segments hence, this study filled in a piece of relevant but missing information in the body of medicine.
The study was an observational, case cross comparison ,retrospective, mixed method research study.Clear pictures, diagram sketches, tables, motion pictures, and laboratory results data of relevant patients case notes were used and the case notes were either summarized or written in full to buttress the point were relevant.
The study found out the following:
1. Stressed single females aged 15-55years are prone to typhoid perforation, arising from salmonella typhi D, and paratyphi A, infections at a lower widal reaction titres of 1in 160, contrary to previous literature, 1in 320 titre; while stressed males 30-55 years are more prone to gastric perforations and at older age >70 years gastric cancers.
2. It enhanced the understanding of the GUT-BRAIN response to pain.while the spino-thalamic reflex releases natural opioids[beta endorphins] to relief pain, the spino adrenergic segment cause the circular and longitudinal smooth muscles of the bowel to contract and shut down peristalsis to limit spread of noxious/injurious substance to the unaffected parts of the gut,the spino-serotogenic response causes rapid fluid accumulation to further dilute the noxious substance in the bowel lumen and the stasis and fluid accumulation lead to vomiting either projectile or non-projectile. Adhesion formation from either omentum majus to posterior abdominal wall, across the bowel, or bowel looping on top of on another, in a new connective tissue web film, are ways on ensuring that the stasis prevents spillage of intestinal content from one segment to another 100%.
3. Although current literature showed salmonella typhi d as resident in mucosa of ileum it failed to show how it reached the peritoneum from there since on its own alone it could not pass beyond the vascular endothelium. Mast cell[TC] group secrete chymase which is capable of dissolving both vascular endothelium as well as epithelium of parietal and visceral peritoneum hence making way for the salmonella organism to reach the peritoneal cavity from the bowel lumen.
4. This study showed that mast cell population density varied in the bowel region viz: 1.small density on anti-mesenteric surface of jejenum or ileum. 2. medium density on distal 1/3 of small intestinal mesentery, 3.maximum density on proximal 1/3 of small intestinal mesentery. So rupture of epithelia as well as vascular endothelium, in all three different locations stated above, were all possible in the three different locations and they are almost always involved in pathology of ruptured intestine.
5. The study reported the following, four cases, which were, first time cases world wide:
1. 53 years old woman with 1st 34 cm of jejenum perforating, at 10, and 33cm from duodeno-jejenal junction, causing serial changes, of adherent omentum majus,adhesive obstruction at jejeno-ileal junction, adhesion of pylorus to liver at neck of gall bladder, plus 3 gall stones of progressively decreasing sizes amongst others.
2. In a 35 years old gravid female, the anterior wall of the uterus perforated and became adherent to gastric epiploicae of the sigmoid colon with dense new adipose tissue formation prior to conception and implantation. Fibromyotic and adenomyotic changes were limited to the 5cm diameter area of the perforation while the rest of the uterine smooth muscle were good.
3. In a 28 year old female, Acute Necrotizing Fascitis, consumed the right ovary and salpinx 100% with dry charcoal residues seen while the left ovary and salpinx were intact and functional.More will come in a subsequent publication,'Advancing the art of medical diagnosis part 5'. Male factor in female infertility and fibrogenesis.
4. Haemolysin virulent factor,from staph aureus has ,beta, alpha, miu, delta antigens, and when transcribed in a distant location like the left breast, from primary site of infection like the vulva vagina region, it causes, multilocular fibrocystic mass brownish color for its alpha or beta variety while the delta variety causes diagona
6.Finally, get your own copy of this book today to get a hold of the moving world of medical science.WE live in a rapidly changing world so don't be left out.
The study was an observational, case cross comparison ,retrospective, mixed method research study.Clear pictures, diagram sketches, tables, motion pictures, and laboratory results data of relevant patients case notes were used and the case notes were either summarized or written in full to buttress the point were relevant.
The study found out the following:
1. Stressed single females aged 15-55years are prone to typhoid perforation, arising from salmonella typhi D, and paratyphi A, infections at a lower widal reaction titres of 1in 160, contrary to previous literature, 1in 320 titre; while stressed males 30-55 years are more prone to gastric perforations and at older age >70 years gastric cancers.
2. It enhanced the understanding of the GUT-BRAIN response to pain.while the spino-thalamic reflex releases natural opioids[beta endorphins] to relief pain, the spino adrenergic segment cause the circular and longitudinal smooth muscles of the bowel to contract and shut down peristalsis to limit spread of noxious/injurious substance to the unaffected parts of the gut,the spino-serotogenic response causes rapid fluid accumulation to further dilute the noxious substance in the bowel lumen and the stasis and fluid accumulation lead to vomiting either projectile or non-projectile. Adhesion formation from either omentum majus to posterior abdominal wall, across the bowel, or bowel looping on top of on another, in a new connective tissue web film, are ways on ensuring that the stasis prevents spillage of intestinal content from one segment to another 100%.
3. Although current literature showed salmonella typhi d as resident in mucosa of ileum it failed to show how it reached the peritoneum from there since on its own alone it could not pass beyond the vascular endothelium. Mast cell[TC] group secrete chymase which is capable of dissolving both vascular endothelium as well as epithelium of parietal and visceral peritoneum hence making way for the salmonella organism to reach the peritoneal cavity from the bowel lumen.
4. This study showed that mast cell population density varied in the bowel region viz: 1.small density on anti-mesenteric surface of jejenum or ileum. 2. medium density on distal 1/3 of small intestinal mesentery, 3.maximum density on proximal 1/3 of small intestinal mesentery. So rupture of epithelia as well as vascular endothelium, in all three different locations stated above, were all possible in the three different locations and they are almost always involved in pathology of ruptured intestine.
5. The study reported the following, four cases, which were, first time cases world wide:
1. 53 years old woman with 1st 34 cm of jejenum perforating, at 10, and 33cm from duodeno-jejenal junction, causing serial changes, of adherent omentum majus,adhesive obstruction at jejeno-ileal junction, adhesion of pylorus to liver at neck of gall bladder, plus 3 gall stones of progressively decreasing sizes amongst others.
2. In a 35 years old gravid female, the anterior wall of the uterus perforated and became adherent to gastric epiploicae of the sigmoid colon with dense new adipose tissue formation prior to conception and implantation. Fibromyotic and adenomyotic changes were limited to the 5cm diameter area of the perforation while the rest of the uterine smooth muscle were good.
3. In a 28 year old female, Acute Necrotizing Fascitis, consumed the right ovary and salpinx 100% with dry charcoal residues seen while the left ovary and salpinx were intact and functional.More will come in a subsequent publication,'Advancing the art of medical diagnosis part 5'. Male factor in female infertility and fibrogenesis.
4. Haemolysin virulent factor,from staph aureus has ,beta, alpha, miu, delta antigens, and when transcribed in a distant location like the left breast, from primary site of infection like the vulva vagina region, it causes, multilocular fibrocystic mass brownish color for its alpha or beta variety while the delta variety causes diagona
6.Finally, get your own copy of this book today to get a hold of the moving world of medical science.WE live in a rapidly changing world so don't be left out.
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Advancing the art of medical diagnoses:3
Advancing the art of medical diagnoses:3
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Product Details
| BN ID: | 2940186575511 |
|---|---|
| Publisher: | Professor Christian Ibekwe |
| Publication date: | 09/01/2022 |
| Series: | Advancing the art of medical diagnosis , #3 |
| Sold by: | Barnes & Noble |
| Format: | eBook |
| File size: | 7 MB |
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