2019 Guide to Medications for the Treatment of Diabetes Mellitus

by John R. White PA-C, PharmD (Editor)

Overview

Medications for the Treatment of Diabetes offers a bridge between drug handbooks and pharmacology texts. Focusing entirely on diabetes drugs, this reference is divided into two sections: 1) Drugs used to manage hyperglycemia and 2) Management of diabetic co-morbidities. The first section includes: -- Pharmacologic Therapy for Type 1 Diabetes -- Management of Hyperglycemia in Type 1 DM– info from practical use of insulin, pathophysiology, treatment strategy -- Insulins- RAIAs, Short-acting insulins, intermediate-acting insulins, LAIAs, Concentrated Insulins, Insulin pumps and patches, inhaled insulins, mixed and mixing insulin, use in Type 1, use in Type 2 -- Pharmacologic Therapy for Type 2 Diabetes -- Management of Hyperglycemia in Type 2- brief overview, pathophysiology, treatment strategy, overview of medications -- Biguanides -- TZDs -- SUs -- Glinides -- SGLT-2 Inhibitors -- AGIs -- DPP-IV inhibitors -- GLP RAs -- Amylin mimetics -- BARs -- DA-2 agonists Each chapter in Section 1 includes: 1. Drug class overview and role in diabetes treatment 2. Pharmacology -- a. Mechanism of action, b. Pharmacokinetics 3. Treatment Advantages/Disadvantages -- a. General for the class, b. When applicable, a discussion of evidence that supports the benefits of using a particular drug in a class over another in the same class (eg, Avandia vs Actos) 4. Therapeutic Considerations -- a. Significant Warnings/Precautions, b. Special Populations, c. Pharmacogenomics, d. Adverse effects and monitoring, e. Drug Interactions, f. Dosage and administration 5. Table with Doses and Dose Adjustments 6. List of important combination products 7. References The second section includes: -- Cardiovascular Disease and Risk Management -- Microvascular Complications and Foot Care -- Medications for the Management of Hypertension -- Medications for the Management of Hyperlipidemia -- Antiplatelet Therapy -- Medications for Smoking Cessation -- Medications for the Management of Neuropathy (peripheral and autonomic) -- Medications for the Management of Nephropathy -- Medications for the Management of Retinopathy -- Medications for the Management of Depression -- Medications for the Management of Hypoglycemia -- Medications for the Management of Obesity -- Immunizations in Patients with Diabetes Each chapter in Section 2 includes: 1. An overview of the condition or problem 2. Goals of treatment 3. Overview of the medications and rationale for the medications used for the problem 4. Overview of each class of medication 5. Overview of combination therapy -- a. first combination, b. second combination 6. Doses and Dose Adjustments for the more salient medications 7. List of important combination products 8. References

Product Details

ISBN-13:	9781580407342
Publisher:	American Diabetes Association
Publication date:	08/06/2019
Sold by:	Barnes & Noble
Format:	eBook
File size:	3 MB
Age Range:	18 Years

About the Author

Volume Editor, John R. White Jr., is chair of the Department of Pharmacotherapy at the Washington State University College of Pharmacy. White is a licensed pharmacist and has a Doctor of Pharmacy (Pharm.D.) degree from Mercer University in Atlanta, GA, and completed a residency and a fellowship in pharmacokinetics/pharmacodynamics at the University of California, San Francisco. He has been affiliated with the WSU College of Pharmacy for more than 20 years. Extensively involved in diabetes research and education since 1987. He is a sought after lecturer on pharmocological research for the treatment of diabetes. In 1998 while a pharmacy professor at WSU, Dr. White completed the University of Washington’s physician assistant training.

Table of Contents

Section I Drugs Used to Manage Hyperglycemia Chapter 1- ADA Standards- Chapter 8- excerpt- Pharmacologic Therapy for Type 1 Diabetes Chapter 2- Management of Hyperglycemia in Type 1 DM– info from practical use of insulin, pathophysiology, treatment strategy- J. Neumiller Chapter 3- Insulins- RAIAs, Short-acting insulins, intermediate-acting insulins, LAIAs, Concentrated Insulins, Insulin pumps and patches, inhaled insulins, mixed and mixing insulin, use in Type 1, use in Type 2- J. Neumiller Chapter 4- ADA Standards- Chapter 8- excerpt- Pharmacologic Therapy for Type 2 Diabetes Chapter 5- Management of Hyperglycemia in Type 2- brief overview, pathophysiology, treatment strategy, overview of medications- J. White Chapter 6- Biguanides- P. Odegard Chapter 7- TZDs- P. Odegard Chapter 8- SUs- L. Kroon Chapter 9- Glinides- L. Kroon Chapter 10- SGLT-2 Inhibitors- J. White Chapter 11- AGIs- K. McKeirnan Chapter 12- DPP-IV inhibitors-K. McKeirnan Chapter 13- GLP RAs- J. Trujillo Chapter 14-Amylin mimetics- J. Trujillo Chapter 15- BARs- C. Buchman Chapter 16- DA-2 agonists- C. Buchman Section II Management of Co-morbidities Chapter 17- ADA Standards- Chapter 9- Cardiovascular Disease and Risk Management Chapter 18- ADA Standards- Chapter 9- Microvascular Complications and Foot Care Chapter 19- Medications for the Management of Hypertension- C. Newsome Chapter 20- Medications for the Management of Hyperlipidemia- C. Newsome Chapter 21- Antiplatelet Therapy- M. Willson Chapter 22- Medications for Smoking Cessation- A. Kim Chapter 23- Medications for the Management of Neuropathy (peripheral and autonomic)- A. Kim Chapter 24- Medications for the Management of Nephropathy- E. Tran Chapter 25- Medications for the Management of Retinopathy- E. Tran Chapter 26- Medications for the Management of Depression- M. Willson Chapter 27- Medications for the Management of Hypoglycemia- M. Giruzzi Chapter 28- Medications for the Management of Obesity- N. Giruzzi Chapter 29- Immunizations in Patients with Diabetes- K. McKeirnan